Bioactive Compound Details
| Compound ID: | B1567700 |
| Source ID: | CHEMBL2396661 |
| Source Type: | Small molecule |
| Compound Name: | ALPELISIB |
| Synonyms: | BYL-719|Alpelisib|Alpelisib|Alpelisib|Alpelisib|Alpelisib|Alpelisib|Alpelisib|Byl-719|BYL719|NVP-BYL719|Piqray|Vijoice|Vijoice |
| Molecular Formula: | C19H22F3N5O2S |
| SMILES: | Cc1nc(NC(=O)N2CCC[C@H]2C(N)=O)sc1-c1ccnc(C(C)(C)C(F)(F)F)c1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |