Bioactive Compound Details
| Compound ID: | B1724957 |
| Source ID: | CHEMBL3218576 |
| Source Type: | Small molecule |
| Compound Name: | COPANLISIB |
| Synonyms: | BAY 80-6946|Bay-80-6946|BAY-80-6946|BAY80-6946|Copanlisib|Copanlisib|Copanlisib|Copanlisib|Copanlisib |
| Molecular Formula: | C23H28N8O4 |
| SMILES: | COc1c(OCCCN2CCOCC2)ccc2c1N=C(NC(=O)c1cnc(N)nc1)N1CCN=C21 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |