Bioactive Compound Details
| Compound ID: | B1763572 |
| Source ID: | CHEMBL3301610 |
| Source Type: | Small molecule |
| Compound Name: | ABEMACICLIB |
| Synonyms: | Abemaciclib|Abemaciclib|Abemaciclib|Abemaciclib|Abemaciclib|Abemaciclib|Abemaciclib|Abemaciclib|Abemaciclib|Ly-2835219|LY-2835219|LY2835219|Verzenio|Verzenios |
| Molecular Formula: | C27H32F2N8 |
| SMILES: | CCN1CCN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |