Bioactive Compound Details
| Compound ID: | B1797534 |
| Source ID: | CHEMBL3348923 |
| Source Type: | Small molecule |
| Compound Name: | TOVORAFENIB |
| Synonyms: | Mln-2480|Biib-024|BIIB-024|BIIB024|DAY-101|DAY101|MLN-2480|Tak 580|Tak-580|TAK-580|Tovorafenib|Tovorafenib|Tovorafenib |
| Molecular Formula: | C17H12Cl2F3N7O2S |
| SMILES: | C[C@@H](NC(=O)c1ncnc(N)c1Cl)c1ncc(C(=O)Nc2cc(C(F)(F)F)c(Cl)cn2)s1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |