Bioactive Compound Details
| Compound ID: | B2197785 |
| Source ID: | CHEMBL3989914 |
| Source Type: | Small molecule |
| Compound Name: | GLESATINIB |
| Synonyms: | Glesatinib|Glesatinib|Glesatinib|MG-90265|MG-90265X|MG90265|MG90265H9|MG90265X|MG90265gly|Mgcd-265|MGCD-265|MGCD265 |
| Molecular Formula: | C31H27F2N5O3S2 |
| SMILES: | COCCNCc1ccc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccc(F)cc5)cc4F)c3s2)nc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |