Bioactive Compound Details
| Compound ID: | B617563 |
| Source ID: | CHEMBL1078178 |
| Source Type: | Small molecule |
| Compound Name: | MOMELOTINIB |
| Synonyms: | CYT-0387|CYT-11387|Cyt-387|CYT-387|CYT387|GS-0387|Momelotinib|Momelotinib|Momelotinib |
| Molecular Formula: | C23H22N6O2 |
| SMILES: | N#CCNC(=O)c1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T50 | Interferon-induced helicase C domain-containing protein 1 | IFIH1 | Hydrolase | Q9BYX4 | IFIH1_HUMAN | Details | |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T50 | Interferon-induced helicase C domain-containing protein 1 | IFIH1 | Hydrolase | Q9BYX4 | IFIH1_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |