Bioactive Compound Details
| Compound ID: | B691867 |
| Source ID: | CHEMBL1229517 |
| Source Type: | Small molecule |
| Compound Name: | VEMURAFENIB |
| Synonyms: | PLX-4032|PLX4032|RG 7204|RG-7204|RO 5185426|RO-51-85426|RO-5185426|Vemurafenib|Vemurafenib|Vemurafenib|Vemurafenib|Vemurafenib|Vemurafenib|Vemurafenib|Vemurafenib|Zelboraf |
| Molecular Formula: | C23H18ClF2N3O3S |
| SMILES: | CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c1F |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |