Bioactive Compound Details
| Compound ID: | B1117804 |
| Source ID: | CHEMBL1738757 |
| Source Type: | Small molecule |
| Compound Name: | REBASTINIB |
| Synonyms: | DCC-2036|Dcc-2036|DCC-2036 FREE BASE|DP-1919|Dp-1919|Rebastinib|Rebastinib|Rebastinib |
| Molecular Formula: | C30H28FN7O3 |
| SMILES: | CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc4ncccc4c3)c(F)c2)ccn1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |