Bioactive Compound Details
| Compound ID: | B1248731 |
| Source ID: | CHEMBL1908360 |
| Source Type: | Small molecule |
| Compound Name: | EVEROLIMUS |
| Synonyms: | Everolimus|40-o-(2-hydroxyethyl)-rapamycin|Afinitor|Afinitor disperz|Certican|Everolimus|Everolimus|Everolimus|Everolimus|Everolimus|Everolimus|Everolimus|Everolimus|Everolimus|RAD 666|RAD-001|RAD-666|RAD001|Sdz rad|SDZ-RAD|Votubia|Zortress |
| Molecular Formula: | C53H83NO14 |
| SMILES: | CO[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@@H](OCCO)[C@H](OC)C2)CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C/1C |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |