Bioactive Compound Details
| Compound ID: | B1265685 |
| Source ID: | CHEMBL1922094 |
| Source Type: | Small molecule |
| Compound Name: | APITOLISIB |
| Synonyms: | Apitolisib|Apitolisib|Apitolisib|G-038390|G-038390.1|GDC-0980|GDC-0980.1|Gne-390|Rg-7422|RG-7422|RG7422 |
| Molecular Formula: | C23H30N8O3S |
| SMILES: | Cc1c(CN2CCN(C(=O)[C@H](C)O)CC2)sc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc12 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |