Bioactive Compound Details
| Compound ID: | B1335704 |
| Source ID: | CHEMBL2017974 |
| Source Type: | Small molecule |
| Compound Name: | BUPARLISIB |
| Synonyms: | Bkm-120|BKM-120|BKM-120NX|BKM120-NX|Buparlisib|Buparlisib|Buparlisib|NVP-BKM-120|NVP-BKM120 |
| Molecular Formula: | C18H21F3N6O2 |
| SMILES: | Nc1cc(C(F)(F)F)c(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)cn1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |