Bioactive Compound Details
| Compound ID: | B1340894 |
| Source ID: | CHEMBL2028663 |
| Source Type: | Small molecule |
| Compound Name: | DABRAFENIB |
| Synonyms: | Dabrafenib|Dabrafenib|Dabrafenib|Dabrafenib|Dabrafenib|Dabrafenib|GSK-2118436|GSK-2118436A|Gsk2118436|GSK2118436A|Tafinlar |
| Molecular Formula: | C23H20F3N5O2S2 |
| SMILES: | CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(N)n2)s1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |