Bioactive Compound Details
| Compound ID: | B1344709 |
| Source ID: | CHEMBL2035187 |
| Source Type: | Small molecule |
| Compound Name: | PACRITINIB |
| Synonyms: | ONX-0803|Pacritinib|Pacritinib|Pacritinib|Pacritinib|Sb-1518|SB-1518|SB1518 |
| Molecular Formula: | C28H32N4O3 |
| SMILES: | C1=N/C2=N/c3ccc(OCCN4CCCC4)c(c3)COC/C=C/COCc3cccc(c3)C(=C1)N2 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |
| T50 | Interferon-induced helicase C domain-containing protein 1 | IFIH1 | Hydrolase | Q9BYX4 | IFIH1_HUMAN | Details |