Bioactive Compound Details
| Compound ID: | B1376100 |
| Source ID: | CHEMBL2103830 |
| Source Type: | Small molecule |
| Compound Name: | FOSTAMATINIB |
| Synonyms: | Fostamatinib|Fostamatinib|Fostamatinib|Fostamatinib|Fostamatinib|R-788|R-788 FREE ACID|R-935788|R-935788 FREE ACID|R788 FREE ACID|R935788 FREE ACID |
| Molecular Formula: | C23H26FN6O9P |
| SMILES: | COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)N(COP(=O)(O)O)C(=O)C(C)(C)O4)n2)cc(OC)c1OC |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |