Bioactive Compound Details
| Compound ID: | B1376110 |
| Source ID: | CHEMBL2103840 |
| Source Type: | Small molecule |
| Compound Name: | DINACICLIB |
| Synonyms: | Dinaciclib|Dinaciclib|Dinaciclib|Mk-7965|SCH 727965|SCH-727965|SCH727965 |
| Molecular Formula: | C21H28N6O2 |
| SMILES: | CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(N3CCCC[C@H]3CCO)nc12 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T36 | Mitochondrial glycerol-3-phosphate dehydrogenase | GPD2 | INHIBITOR | Oxidoreductase | P43304 | GPD2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |