Bioactive Compound Details
| Compound ID: | B1376112 |
| Source ID: | CHEMBL2103842 |
| Source Type: | Small molecule |
| Compound Name: | VARLITINIB |
| Synonyms: | AR-00334543|ARRY-334543|ARRY-543|ASLAN-001|ASLAN001|Varlitinib|Varlitinib|Varlitinib |
| Molecular Formula: | C22H19ClN6O2S |
| SMILES: | C[C@@H]1COC(Nc2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)=N1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |