Bioactive Compound Details
| Compound ID: | B1376121 |
| Source ID: | CHEMBL2103851 |
| Source Type: | Small molecule |
| Compound Name: | AMUVATINIB |
| Synonyms: | Amuvatinib|Amuvatinib|Amuvatinib|HPK 56|HPK-56|HPK56|MP 470|MP-470|MP470 |
| Molecular Formula: | C23H21N5O3S |
| SMILES: | S=C(NCc1ccc2c(c1)OCO2)N1CCN(c2ncnc3c2oc2ccccc23)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |