Bioactive Compound Details
| Compound ID: | B1377998 |
| Source ID: | CHEMBL2105728 |
| Source Type: | Small molecule |
| Compound Name: | CRENOLANIB |
| Synonyms: | ARO 002|ARO-002|CP 868596|CP-868,596|CP-868596|Crenolanib|Crenolanib|Crenolanib |
| Molecular Formula: | C26H29N5O2 |
| SMILES: | CC1(COc2ccc3c(c2)ncn3-c2ccc3cccc(N4CCC(N)CC4)c3n2)COC1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |