Bioactive Compound Details
| Compound ID: | B1378029 |
| Source ID: | CHEMBL2105759 |
| Source Type: | Small molecule |
| Compound Name: | BARICITINIB |
| Synonyms: | Baricitinib|Baricitinib|Baricitinib|Baricitinib|Baricitinib|Baricitinib|Baricitinib|Baricitinib|Baricitinib phosphate|Baricitinib phosphate salt|Baricitinib|INCB-028050|Incb-28050|INCB028050|LY-3009104|LY3009104|Olumiant |
| Molecular Formula: | C16H17N7O2S |
| SMILES: | CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3ncnc4[nH]ccc34)cn2)C1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |