Bioactive Compound Details
| Compound ID: | B1448219 |
| Source ID: | CHEMBL2216870 |
| Source Type: | Small molecule |
| Compound Name: | IDELALISIB |
| Synonyms: | CAL-101|GS-11CAL-101|CAL-101|GS-1101|Idelalisib|Idelalisib|Idelalisib|Idelalisib|Idelalisib|Idelalisib|Idelalisib|Zydelig |
| Molecular Formula: | C22H18FN7O |
| SMILES: | CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |