Bioactive Compound Details
| Compound ID: | B1592335 |
| Source ID: | CHEMBL3039517 |
| Source Type: | Small molecule |
| Compound Name: | RABUSERTIB |
| Synonyms: | IC-83|Ly-2603618|LY-2603618|LY2603618|Rabusertib|Rabusertib|Rabusertib |
| Molecular Formula: | C18H22BrN5O3 |
| SMILES: | Cc1cnc(NC(=O)Nc2cc(Br)c(C)cc2OC[C@@H]2CNCCO2)cn1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |