Bioactive Compound Details
| Compound ID: | B1677558 |
| Source ID: | CHEMBL3188267 |
| Source Type: | Small molecule |
| Compound Name: | CAPMATINIB |
| Synonyms: | Capmatinib|Capmatinib|Capmatinib|Capmatinib|INC-280|INC280|Incb-28060|INCB-28060|INCB-28060 FREE BASE|NVP-INC280|NVP-INC280-NX|NYP-INC280-NX |
| Molecular Formula: | C23H17FN6O |
| SMILES: | CNC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1F |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |