Bioactive Compound Details
| Compound ID: | B1763569 |
| Source ID: | CHEMBL3301607 |
| Source Type: | Small molecule |
| Compound Name: | FILGOTINIB |
| Synonyms: | Filgotinib|Filgotinib|Filgotinib|Filgotinib|G-146034|G146034|Glpg-0634|GLPG0634|GS-6034 FREE BASE |
| Molecular Formula: | C21H23N5O3S |
| SMILES: | O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |