Bioactive Compound Details
| Compound ID: | B1763574 |
| Source ID: | CHEMBL3301612 |
| Source Type: | Small molecule |
| Compound Name: | ENCORAFENIB |
| Synonyms: | Braftovi|Encorafenib|Encorafenib|Encorafenib|Encorafenib|Encorafenib|Encorafenib|Encorafenib|Encorafenib|Lgx-818|Lgx818|NVP-LGX-818-NXA|NVP-LGX818|NVP-LGX818-NXA |
| Molecular Formula: | C22H27ClFN7O4S |
| SMILES: | COC(=O)N[C@@H](C)CNc1nccc(-c2cn(C(C)C)nc2-c2cc(Cl)cc(NS(C)(=O)=O)c2F)n1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |