Bioactive Compound Details
| Compound ID: | B1790692 |
| Source ID: | CHEMBL3334567 |
| Source Type: | Small molecule |
| Compound Name: | SAVOLITINIB |
| Synonyms: | Azd-6094|AZD-6094|AZD6094|HMPL-504|Savolitinib|Savolitinib|Savolitinib|Volitinib |
| Molecular Formula: | C17H15N9 |
| SMILES: | C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(-c3cnn(C)c3)nc21 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |