Bioactive Compound Details
| Compound ID: | B1832976 |
| Source ID: | CHEMBL3402762 |
| Source Type: | Small molecule |
| Compound Name: | TEPOTINIB |
| Synonyms: | EMD 1214063|Emd-1214063|EMD-1214063|EMD1214063|MSC-2156119|MSC-2156119J|MSC2156119|Tepotinib|Tepotinib|Tepotinib|Tepotinib |
| Molecular Formula: | C29H28N6O2 |
| SMILES: | CN1CCC(COc2cnc(-c3cccc(Cn4nc(-c5cccc(C#N)c5)ccc4=O)c3)nc2)CC1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |