Bioactive Compound Details
| Compound ID: | B1926832 |
| Source ID: | CHEMBL3544983 |
| Source Type: | Small molecule |
| Compound Name: | TESEVATINIB |
| Synonyms: | EXEL-7647|KD-019|KD-020|KD019|Tesevatinib|Tesevatinib|Tesevatinib|Xl-647|XL647 |
| Molecular Formula: | C24H25Cl2FN4O2 |
| SMILES: | COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@@H]2CN(C)C[C@@H]2C1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |