Bioactive Compound Details
| Compound ID: | B1926959 |
| Source ID: | CHEMBL3545110 |
| Source Type: | Small molecule |
| Compound Name: | RIBOCICLIB |
| Synonyms: | Lee-011|LEE-011|LEE-011A|LEE011|LEE011A|NVP-LEE011|Ribociclib|Ribociclib|Ribociclib|Ribociclib|Ribociclib |
| Molecular Formula: | C23H30N8O |
| SMILES: | CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CCCC1 |
| Molecular Species: | BASE |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |