Bioactive Compound Details
| Compound ID: | B1927003 |
| Source ID: | CHEMBL3545154 |
| Source Type: | Small molecule |
| Compound Name: | POZIOTINIB |
| Synonyms: | HM 781-36|HM 781-36B|HM-781-36|Hm-781-36b|HM-781-36B|HM781-36B|NOV-1201|NOV-120101|Poziotinib|Poziotinib|Poziotinib |
| Molecular Formula: | C23H21Cl2FN4O3 |
| SMILES: | C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(Cl)c(Cl)c4F)ncnc3cc2OC)CC1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |