Bioactive Compound Details
| Compound ID: | B2197739 |
| Source ID: | CHEMBL3989868 |
| Source Type: | Small molecule |
| Compound Name: | TUCATINIB |
| Synonyms: | ARRY-380|Irbinitinib|MK-7119|Ont-380|ONT-380|Tucatinib|Tucatinib|Tucatinib|Tucatinib|Tucatinib|Tucatinib|Tukysa |
| Molecular Formula: | C26H24N8O2 |
| SMILES: | Cc1cc(Nc2ncnc3ccc(NC4=NC(C)(C)CO4)cc23)ccc1Oc1ccn2ncnc2c1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |