Bioactive Compound Details
| Compound ID: | B363089 |
| Source ID: | CHEMBL415049 |
| Source Type: | Small molecule |
| Compound Name: | BARASERTIB |
| Synonyms: | AZD 1152|Azd-1152|AZD-1152|AZD1152|Barasertib|Barasertib (who-dd)|Barasertib |
| Molecular Formula: | C26H31FN7O6P |
| SMILES: | CCN(CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1)CCOP(=O)(O)O |
| Molecular Species: | ZWITTERION |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |