Bioactive Compound Details
| Compound ID: | B692515 |
| Source ID: | CHEMBL1230165 |
| Source Type: | Small molecule |
| Compound Name: | SILMITASERTIB |
| Synonyms: | CX-4945|CX 4945|Cx-4945|Cx-4945 free acid|CX4945|Silmitasertib|Silmitasertib |
| Molecular Formula: | C19H12ClN3O2 |
| SMILES: | O=C(O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc12 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |