Bioactive Compound Details
| Compound ID: | B715901 |
| Source ID: | CHEMBL1289494 |
| Source Type: | Small molecule |
| Compound Name: | TIVOZANIB |
| Synonyms: | ASP-4130|AV-951|Fotivda|KIL8951|Krn-951|KRN-951|Kil-8951|Tivozanib|Tivozanib|Tivozanib|Tivozanib|Tivozanib |
| Molecular Formula: | C22H19ClN4O5 |
| SMILES: | COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |