Research Articles
Research articles concerning CKD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in CKDdb are presented with knowledge graphs.
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Diabetes mellitus148 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00135 | 20651284 | Circ Res | Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes. | 2010 | Details |
| A00137 | 21186350 | Nat Genet | Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. | 2011 | Details |
| A00138 | 21364139 | JAMA | Functional variants of the HMGA1 gene and type 2 diabetes mellitus. | 2011 | Details |
| A00140 | 21673050 | Genome Res | Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism. | 2012 | Details |
| A00141 | 22286214 | Nat Genet | Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes. | 2012 | Details |
| A00144 | 24193408 | Pflugers Arch | Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin. | 2015 | Details |
| A00145 | 24390345 | Nature | Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. | 2014 | Details |
| A00146 | 24463454 | J Clin Invest | Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients. | 2014 | Details |
| A00149 | 24897035 | Kidney Int | The HNF1B score is a simple tool to select patients for HNF1B gene analysis. | 2015 | Details |
| A00150 | 24904092 | J Am Soc Nephrol | Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials. | 2015 | Details |
| A00152 | 25349199 | J Am Soc Nephrol | A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. | 2015 | Details |
| A00153 | 25536396 | Nat Rev Nephrol | HNF1B-associated renal and extra-renal disease-an expanding clinical spectrum. | 2015 | Details |
| A00156 | 25786098 | Kidney Int | Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. | 2016 | Details |
| A00157 | 25894829 | Nat Med | Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. | 2015 | Details |
| A00160 | 26551672 | Nat Genet | Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. | 2016 | Details |
| A00162 | 2695375 | Diabetes | Distribution of in vivo insulin action in Pima Indians as mixture of three normal distributions. | 1990 | Details |
| A00163 | 27188453 | Eur J Endocrinol | Clinical and genetic characterization of congenital hyperinsulinism in Spain. | 2017 | Details |
| A00164 | 27398621 | Nature | The genetic architecture of type 2 diabetes. | 2016 | Details |
| A00165 | 27484667 | Nephrol Dial Transplant | Prognostic enrichment design in clinical trials for autosomal dominant polycystic kidney disease: the HALT-PKD clinical trial. | 2018 | Details |
| A00167 | 27896077 | Mol Genet Metab Rep | Sequencing analysis of insulin receptor defects and detection of two novel mutations in <i>INSR</i> gene. | 2020 | Details |
| A00168 | 27908292 | Orphanet J Rare Dis | Conservatively treated Congenital Hyperinsulinism (CHI) due to K-ATP channel gene mutations: reducing severity over time. | 2017 | Details |
| A00171 | 28838955 | J Am Soc Nephrol | Bosutinib versus Placebo for Autosomal Dominant Polycystic Kidney Disease. | 2017 | Details |
| A00172 | 29361385 | J Formos Med Assoc | Mutation screening of INS and KCNJ11 genes in Taiwanese children with type 1B diabetic onset before the age of 5 years. | 2018 | Details |
| A00174 | 29471960 | Nefrologia (Engl Ed) | Overview of autosomal dominant polycystic kidney disease in the south of Spain. | 2018 | Details |
| A00175 | 29674338 | Clin J Am Soc Nephrol | Prevalence of Hypertension in Children with Early-Stage ADPKD. | 2019 | Details |
| A00176 | 29751826 | BMC Med Genet | Possible association between ABCC8 C49620T polymorphism and type 2 diabetes in a Nigerian population. | 2019 | Details |
| A00177 | 30422235 | JAMA | Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease: The DIPAK 1 Randomized Clinical Trial. | 2018 | Details |
| A00178 | 30927425 | Hum Reprod | Factors influencing the clinical outcome of preimplantation genetic testing for polycystic kidney disease. | 2020 | Details |
| A00185 | 32634120 | JCI Insight | The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD. | 2021 | Details |
| A00186 | 32939031 | Genet Med | Clinical impact of genomic testing in patients with suspected monogenic kidney disease. | 2021 | Details |
| A00187 | 33097957 | Nephrol Dial Transplant | Mutations in transcription factor CP2-like 1 may cause a novel syndrome with distal renal tubulopathy in humans. | 2021 | Details |
| A00188 | 33141305 | Clin Exp Nephrol | Effect of tolvaptan on renal involvement in patients with autosomal dominant polycystic kidney disease according to different gene mutations. | 2021 | Details |
| A00189 | 33164752 | Elife | The heteromeric PC-1/PC-2 polycystin complex is activated by the PC-1 N-terminus. | 2021 | Details |
| A00191 | 33853507 | Nucleosides Nucleotides Nucleic Acids | Association of common genetic variants of <i>KCNJ11</i> gene with the risk of type 2 diabetes mellitus. | 2024 | Details |
| A00192 | 34145744 | Am J Med Genet A | Homozygous WNT9B variants in two families with bilateral renal agenesis/hypoplasia/dysplasia. | 2022 | Details |
| A00193 | 36646975 | Pediatr Nephrol | Dual diagnosis of autosomal dominant polycystic kidney disease and sickle cell disease in a teenage male. | 2023 | Details |
| A00194 | 39660790 | J Med Econ | Cost-effectiveness analysis of radiofrequency renal denervation for uncontrolled hypertension in Canada. | 2024 | Details |
| A00195 | 39684653 | Int J Mol Sci | Pharmacological Nephroprotection in Chronic Kidney Disease Patients with Type 2 Diabetes Mellitus-Clinical Practice Position Statement of the Polish Society of Nephrology. | 2024 | Details |
| A00196 | 39704168 | JCI Insight | Fasting substrates predict chronic kidney disease progression in CREDENCE trial patients with type 2 diabetes. | 2024 | Details |
| A00197 | 39731488 | Malays J Pathol | MACB CKD Task Force updated recommendations for reporting estimated glomerular filtration rate and albuminuria in adults. | 2024 | Details |
| A00198 | 39746795 | Ren Fail | Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production. | 2025 | Details |
| A00199 | 39783822 | J Med Econ | Cost-effectiveness of finerenone therapy for patients with chronic kidney disease and type 2 diabetes in England & Wales: results of the FINE-CKD model. | 2025 | Details |
| A00200 | 39804512 | Langenbecks Arch Surg | A hypocaloric protein-rich diet before metabolic surgery improves liver function in patients with obesity and diabetes : A secondary analysis of a randomized clinical trial. | 2025 | Details |
| A00201 | 39806375 | Cardiovasc Diabetol | Echocardiographic phenotypes of diabetic myocardial disorder: evolution over 15 months follow-up in the ARISE-HF trial. | 2025 | Details |
| A00202 | 39816051 | Narra J | Effects of cholecalciferol supplementation on depressive symptoms, C-peptide, serotonin, and neurotrophin-3 in type 2 diabetes mellitus: A double-blind, randomized, placebo-controlled trial. | 2025 | Details |
| A00204 | 39873191 | Gut Microbes | Gut microbiota modulation via fecal microbiota transplantation mitigates hyperoxaluria and calcium oxalate crystal depositions induced by high oxalate diet. | 2025 | Details |
| A00205 | 39903475 | Ann Med | An overview of downhill esophageal varices: a challenge for medical practice. | 2025 | Details |
| A00207 | 39957366 | Ren Fail | Public interest in chronic kidney disease and dialysis: a 20-year data analysis. | 2025 | Details |