Repositioning Candidates
Repositioning candidates for CKD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and CKD-associated disease in CKDdb are presented with knowledge graphs.
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546 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0301 | DB01011 | approved; investigational | small molecule | Metyrapone | Details | |
| R0302 | DB01012 | approved | small molecule | Cinacalcet | Details | |
| R0303 | DB01015 | approved | small molecule | Sulfamethoxazole | Details | |
| R0304 | DB01019 | approved | small molecule | Bethanechol | Details | |
| R0305 | DB01022 | approved; investigational | small molecule | Phylloquinone | Details | |
| R0306 | DB01023 | approved; investigational | small molecule | Felodipine | Details | |
| R0307 | DB01024 | approved | small molecule | Mycophenolic acid | Details | |
| R0308 | DB01025 | approved; investigational; withdrawn | small molecule | Amlexanox | Details | |
| R0309 | DB01029 | approved; investigational | small molecule | Irbesartan | Details | |
| R0310 | DB01032 | approved; investigational | small molecule | Probenecid | Details | |
| R0311 | DB01039 | approved | small molecule | Fenofibrate | Details | |
| R0312 | DB01041 | approved; investigational; withdrawn | small molecule | Thalidomide | Details | |
| R0313 | DB01050 | approved | small molecule | Ibuprofen | Details | |
| R0314 | DB01053 | approved; vet_approved | small molecule | Benzylpenicillin | Details | |
| R0315 | DB01060 | approved; vet_approved | small molecule | Amoxicillin | Details | |
| R0316 | DB01065 | approved; nutraceutical; vet_approved | small molecule | Melatonin | Details | |
| R0317 | DB01067 | approved; investigational | small molecule | Glipizide | Details | |
| R0318 | DB01069 | approved; investigational | small molecule | Promethazine | Details | |
| R0319 | DB01075 | approved; investigational | small molecule | Diphenhydramine | Details | |
| R0320 | DB01076 | approved | small molecule | Atorvastatin | Details | |
| R0321 | DB01080 | approved | small molecule | Vigabatrin | Details | |
| R0322 | DB01082 | approved; vet_approved | small molecule | Streptomycin | Details | |
| R0323 | DB01083 | approved; investigational | small molecule | Orlistat | Details | |
| R0324 | DB01085 | approved; investigational | small molecule | Pilocarpine | Details | |
| R0325 | DB01086 | approved; investigational | small molecule | Benzocaine | Details | |
| R0326 | DB01093 | approved; vet_approved | small molecule | Dimethyl sulfoxide | Details | |
| R0327 | DB01100 | approved | small molecule | Pimozide | Details | |
| R0328 | DB01104 | approved | small molecule | Sertraline | Details | |
| R0329 | DB01110 | approved; investigational; vet_approved | small molecule | Miconazole | Details | |
| R0330 | DB01115 | approved | small molecule | Nifedipine | Details | |
| R0331 | DB01118 | approved; investigational | small molecule | Amiodarone | Details | |
| R0332 | DB01119 | approved | small molecule | Diazoxide | Details | |
| R0333 | DB01120 | approved | small molecule | Gliclazide | Details | |
| R0334 | DB01124 | approved; investigational | small molecule | Tolbutamide | Details | |
| R0335 | DB01126 | approved; investigational | small molecule | Dutasteride | Details | |
| R0336 | DB01132 | approved; investigational | small molecule | Pioglitazone | Details | |
| R0337 | DB01136 | approved; investigational | small molecule | Carvedilol | Details | |
| R0338 | DB01137 | approved; investigational | small molecule | Levofloxacin | Details | |
| R0339 | DB01140 | approved; vet_approved; withdrawn | small molecule | Cefadroxil | Details | |
| R0340 | DB01156 | approved | small molecule | Bupropion | Details | |
| R0341 | DB01162 | approved | small molecule | Terazosin | Details | |
| R0342 | DB01165 | approved | small molecule | Ofloxacin | Details | |
| R0343 | DB01166 | approved; investigational | small molecule | Cilostazol | Details | |
| R0344 | DB01167 | approved; investigational | small molecule | Itraconazole | Details | |
| R0345 | DB01178 | approved; investigational; withdrawn | small molecule | Chlormezanone | Details | |
| R0346 | DB01183 | approved; vet_approved | small molecule | Naloxone | Details | |
| R0347 | DB01184 | approved; investigational; vet_approved | small molecule | Domperidone | Details | |
| R0348 | DB01188 | approved; investigational | small molecule | Ciclopirox | Details | |
| R0349 | DB01189 | approved | small molecule | Desflurane | Details | |
| R0350 | DB01190 | approved; vet_approved | small molecule | Clindamycin | Details | |
| R0351 | DB01191 | approved; illicit; investigational; withdrawn | small molecule | Dexfenfluramine | Details | |
| R0352 | DB01197 | approved | small molecule | Captopril | Details | |
| R0353 | DB01198 | approved | small molecule | Zopiclone | Details | |
| R0354 | DB01200 | approved; investigational | small molecule | Bromocriptine | Details | |
| R0355 | DB01211 | approved | small molecule | Clarithromycin | Details | |
| R0356 | DB01212 | approved | small molecule | Ceftriaxone | Details | |
| R0357 | DB01217 | approved; investigational | small molecule | Anastrozole | Details | |
| R0358 | DB01219 | approved; investigational | small molecule | Dantrolene | Details | |
| R0359 | DB01222 | approved | small molecule | Budesonide | Details | |
| R0360 | DB01224 | approved | small molecule | Quetiapine | Details | |
| R0361 | DB01229 | approved; vet_approved | small molecule | Paclitaxel | Details | |
| R0362 | DB01233 | approved; investigational | small molecule | Metoclopramide | Details | |
| R0363 | DB01234 | approved; investigational; vet_approved | small molecule | Dexamethasone | Details | |
| R0364 | DB01236 | approved; vet_approved | small molecule | Sevoflurane | Details | |
| R0365 | DB01238 | approved; investigational | small molecule | Aripiprazole | Details | |
| R0366 | DB01240 | approved | small molecule | Epoprostenol | Details | |
| R0367 | DB01251 | approved; investigational | small molecule | Gliquidone | Details | |
| R0368 | DB01254 | approved; investigational | small molecule | Dasatinib | Details | |
| R0369 | DB01259 | approved; investigational | small molecule | Lapatinib | Details | |
| R0370 | DB01264 | approved | small molecule | Darunavir | Details | |
| R0371 | DB01268 | approved; investigational | small molecule | Sunitinib | Details | |
| R0372 | DB01275 | approved | small molecule | Hydralazine | Details | |
| R0373 | DB01283 | approved; investigational | small molecule | Lumiracoxib | Details | |
| R0374 | DB01296 | approved; investigational | small molecule | Glucosamine | Details | |
| R0375 | DB01327 | approved | small molecule | Cefazolin | Details | |
| R0376 | DB01339 | approved; investigational | small molecule | Vecuronium | Details | |
| R0377 | DB01340 | approved | small molecule | Cilazapril | Details | |
| R0378 | DB01348 | approved | small molecule | Spirapril | Details | |
| R0379 | DB01364 | approved | small molecule | Ephedrine | Details | |
| R0380 | DB01392 | approved; investigational; vet_approved | small molecule | Yohimbine | Details | |
| R0381 | DB01393 | approved; investigational | small molecule | Bezafibrate | Details | |
| R0382 | DB01394 | approved | small molecule | Colchicine | Details | |
| R0383 | DB01395 | approved | small molecule | Drospirenone | Details | |
| R0384 | DB01403 | approved; investigational | small molecule | Methotrimeprazine | Details | |
| R0385 | DB01407 | approved; investigational; vet_approved | small molecule | Clenbuterol | Details | |
| R0386 | DB01412 | investigational | small molecule | Theobromine | Details | |
| R0387 | DB01413 | approved; investigational | small molecule | Cefepime | Details | |
| R0388 | DB01436 | approved; nutraceutical | small molecule | Alfacalcidol | Details | |
| R0389 | DB01452 | approved; illicit; investigational | small molecule | Diamorphine | Details | |
| R0390 | DB01577 | approved; illicit | small molecule | Metamfetamine | Details | |
| R0391 | DB01582 | approved; investigational; vet_approved | small molecule | Sulfamethazine | Details | |
| R0392 | DB01586 | approved; investigational | small molecule | Ursodeoxycholic acid | Details | |
| R0393 | DB01599 | approved; investigational | small molecule | Probucol | Details | |
| R0394 | DB01601 | approved | small molecule | Lopinavir | Details | |
| R0395 | DB01606 | approved | small molecule | Tazobactam | Details | |
| R0396 | DB01611 | approved | small molecule | Hydroxychloroquine | Details | |
| R0397 | DB01618 | approved | small molecule | Molindone | Details | |
| R0398 | DB01623 | approved | small molecule | Thiothixene | Details | |
| R0399 | DB01638 | approved | small molecule | Sorbitol | Details | |
| R0400 | DB01645 | investigational | small molecule | Genistein | Details |