CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C06101 | BRD-K48329353 | 6,_7-dehydro-17-acetoxy-progesterone | steroidal progestin | Details | ||
| C06102 | BRD-K00656370 | 6-aminochrysene | transferase inhibitor | Details | ||
| C06103 | BRD-K30284967 | 6-aminopenicillanic-acid | Details | |||
| C06104 | BRD-K62929068 | 6-benzylaminopurine | purinergic receptor activator | Details | ||
| C06105 | BRD-K34663752 | 6-chloromelatonin | MTNR1A|MTNR1B | melatonin receptor agonist | Details | |
| C06106 | BRD-K49236613 | 6-iodo-nordihydrocapsaicin | TRPV1 | TRPV antagonist | Details | |
| C06107 | BRD-K77756533 | 7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one | Details | |||
| C06108 | BRD-K65377893 | 7-aminocephalosporanic-acid | beta lactamase inhibitor | Details | ||
| C06109 | BRD-K84214706 | 7-chlorokynurenic-acid | GRIN1|GRIN2A|GRIN2B|GRIN2C | glutamate receptor antagonist | Details | |
| C06110 | BRD-A18795974 | 7-hydroxy-DPAT | DRD2|DRD3 | dopamine receptor agonist | Details | |
| C06111 | BRD-A01295252 | 7-hydroxy-PIPAT | DRD3 | dopamine receptor ligand | Details | |
| C06112 | BRD-K45293975 | 7-hydroxystaurosporine | CHEK1|MARK3|PDPK1 | CDK inhibitor; CHK inhibitor; PKC inhibitor | Details | |
| C06113 | BRD-K07785030 | 7-keto-DHEA | steroid | Details | ||
| C06114 | BRD-K53156626 | 7-methoxytacrine | ACHE | acetylcholinesterase inhibitor | Details | |
| C06115 | BRD-K41592905 | 7-methylxanthine | adenosine receptor antagonist | Details | ||
| C06116 | BRD-K04430056 | 7-nitroindazole | NOS1|NOS2|NOS3 | nitric oxide synthase inhibitor | Details | |
| C06117 | BRD-A09554849 | 8-bromo-cAMP | PKA activator | Details | ||
| C06118 | BRD-A00077618 | 8-bromo-cGMP | PRKG1 | PKA activator | Details | |
| C06119 | BRD-A48015106 | 8-hydroxy-DPAT | CDK1|CHEK1|CHEK2|GSK3B|HTR5A|HTR7|LCK|MAPK14|MARK1|PDPK1|PRKCA|PRKCB|PRKCD|PRKCE|PRKCG | serotonin receptor agonist | Details | |
| C06120 | BRD-A60594020 | 8-hydroxy-PIPAT | DRD2|DRD3 | dopamine receptor ligand | Details | |
| C06121 | BRD-A07232941 | 8-M-PDOT | MTNR1A|MTNR1B | melatonin receptor agonist | Details | |
| C06122 | BRD-K03044000 | 80841-78-7 | Details | |||
| C06123 | BRD-K00535541 | 9-aminoacridine | Details | |||
| C06124 | BRD-K09291936 | 9-aminocamptothecin | TOP1 | topoisomerase inhibitor | Details | |
| C06125 | BRD-K62607075 | 9-anthracenecarboxylic-acid | ANO1|CLCN1 | Details |