Bioactive Compound Details
| Compound ID: | B630975 |
| Source ID: | CHEMBL1084546 |
| Source Type: | Small molecule |
| Compound Name: | PF-00562271 |
| Synonyms: | PF-562271|PF 562271|Pf-00562271|Pf-562271 besilate |
| Molecular Formula: | C21H20F3N7O3S |
| SMILES: | CN(c1ncccc1CNc1nc(Nc2ccc3c(c2)CC(=O)N3)ncc1C(F)(F)F)S(C)(=O)=O |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T20 | Hepatocyte nuclear factor 4-alpha | HNF4A | ACTIVATOR | Target is a single protein chain | P41235 | HNF4A_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T50 | Interferon-induced helicase C domain-containing protein 1 | IFIH1 | Hydrolase | Q9BYX4 | IFIH1_HUMAN | Details | |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T16 | Phospholipase C-gamma-2 | PLCG2 | Hydrolase | P16885 | PLCG2_HUMAN | Details | |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T30 | TP53-regulating kinase | TP53RK | Target is a single protein chain | Q96S44 | TP53RK_HUMAN | Details | |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |
| T28 | Interleukin-6 | IL6 | ANTAGONIST; INHIBITOR; BINDING AGENT | Target is a single protein chain | P05231 | IL6_HUMAN | Details |
| T09 | Serine/threonine-protein kinase AKT2 | AKT2 | INHIBITOR | Target is a single protein chain | P31751 | AKT2_HUMAN | Details |
| T01 | Insulin receptor | INSR | AGONIST; INHIBITOR | Target is a single protein chain | P06213 | INSR_HUMAN | Details |
| T07 | Potassium channel, inwardly rectifying, subfamily J, member 11 | KCNJ11 | OPENER | Target is a single protein chain | Q14654 | KCNJ11_HUMAN | Details |
| T06 | Sulfonylurea receptor 1 | ABCC8 | Target is a single protein chain | Q09428 | ABCC8_HUMAN | Details |