CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C02501 | BRD-K12198961 | G007-LK | TNKS|TNKS2 | tankyrase inhibitor | Details | |
| C02502 | BRD-K27737647 | H-89 | GSG2|PKIA|PRKACA | PKA inhibitor | Details | |
| C02503 | BRD-K05434375 | HA-1004 | calcium channel blocker | Details | ||
| C02504 | BRD-K64452997 | HA-130 | ENPP2 | autotaxin inhibitor | Details | |
| C02505 | BRD-A13807286 | HA-14-1 | BCL2 | BCL inhibitor | Details | |
| C02506 | BRD-K58046914 | HA-966-(R)-(+) | GRIA1 | glutamate receptor agonist | Details | |
| C02507 | BRD-K41304947 | HA-966-(S)-(-) | GRIA1 | glutamate receptor antagonist | Details | |
| C02508 | BRD-K68091065 | halazone | Details | |||
| C02509 | BRD-A88138582 | halcinonide | NR3C1 | glucocorticoid receptor agonist | Details | |
| C02510 | BRD-K65877271 | halobetasol-propionate | NR3C1|PLA2G1B | glucocorticoid receptor agonist | Details | |
| C02511 | BRD-A51964809 | halofantrine | KCNH2|KCNN4 | antimalarial agent | Details | |
| C02512 | BRD-K54247840 | halofuginone | COL1A1|MMP2 | collagenase inhibitor | Details | |
| C02513 | BRD-K50055394 | halopemide | PLD1|PLD2 | phospholipase inhibitor | Details | |
| C02514 | BRD-K67783091 | haloperidol | DRD1|DRD2|DRD3|DRD4|DRD5|GRIN2B|HRH1|HTR1A|HTR1D|HTR2A|HTR2B|HTR7|KCNH1 | dopamine receptor antagonist | Details | |
| C02515 | BRD-K80859331 | haloperidol-decanoate | DRD2|DRD3|DRD4|HTR2A | psychoactive drug | Details | |
| C02516 | BRD-K13238168 | haloprogin | other antifungal | Details | ||
| C02517 | BRD-A20550616 | halothane | ATP2C1|ATP5D|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GLRA1|GLRB|GNG2|GRIN2A|GRIN3A|GRIN3B|KCNJ3|KCNJ6|KCNK10|KCNK12|KCNK13|KCNK15|KCNK18|KCNK2|KCNK3|KCNK9|KCNMA1|KCNN4|MT-ND1|NPSR1|RHO | glutamate receptor antagonist | Details | |
| C02518 | BRD-K12630395 | harmane | MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C02519 | BRD-K96358241 | harringtonine | protein synthesis inhibitor | Details | ||
| C02520 | BRD-K18163608 | HA14-1 | BCL2 | BCL inhibitor | Details | |
| C02521 | BRD-K73815512 | HC-030031 | TRPA1 | TRPA1 channel blocker | Details | |
| C02522 | BRD-K03391209 | HC-067047 | TRPV4 | transient receptor potential channel antagonist | Details | |
| C02523 | BRD-K49788188 | heclin | NEDD4|SMURF2|WWP1 | ubiquitin ligase inhibitor | Details | |
| C02524 | BRD-K34672903 | HEMADO | ADORA1|ADORA2A|ADORA2B|ADORA3 | Details | ||
| C02525 | BRD-A44995766 | hematoporphyrin | Details | |||
| C02526 | BRD-K78342372 | hematoxylin | Details | |||
| C02527 | BRD-M75036822 | hemin | enzyme inducer | Details | ||
| C02528 | BRD-K43639297 | hemoglobin-modulators-1 | hemoglobin modulator | Details | ||
| C02529 | BRD-K15231341 | hemomex-s | PPARG | Details | ||
| C02530 | BRD-A32988684 | heptaminol | vasoconstrictor | Details | ||
| C02531 | BRD-K89709433 | HER2-Inhibitor-1 | EGFR inhibitor | Details | ||
| C02532 | BRD-K58122457 | hesperadin | AURKB | Aurora kinase inhibitor | Details | |
| C02533 | BRD-K30553453 | hesperetin | DGAT1|MTTP|SOAT1|SOAT2 | ACAT inhibitor | Details | |
| C02534 | BRD-K38903228 | hesperidin | CACNA1B | flavanone glycoside | Details | |
| C02535 | BRD-A27828834 | hetacillin | bacterial cell wall synthesis inhibitor | Details | ||
| C02536 | BRD-K99792991 | hexachlorophene | GLUD1|SDHD | potassium channel activator | Details | |
| C02537 | BRD-K10598093 | hexamethonium | CHRNA2|CHRNA3|CHRNA4|CHRNA6 | cholinergic receptor antagonist | Details | |
| C02538 | BRD-K04710043 | hexamethylenebisacetamide | AKT1 | AKT inhibitor; differentiation inducer; NFKB pathway inhibitor | Details | |
| C02539 | BRD-K73753850 | hexaminolevulinate | Details | |||
| C02540 | BRD-K70007857 | hexasodium-phytate | Details | |||
| C02541 | BRD-A01078468 | hexestrol | AKR1C1|ESR1|ESR2 | synthetic estrogen | Details | |
| C02542 | BRD-A18605525 | hexetidine | local anesthetic | Details | ||
| C02543 | BRD-A63267145 | hexonic-acid | Details | |||
| C02544 | BRD-A33894669 | hexoprenaline | ADRB2 | adrenergic receptor agonist | Details | |
| C02545 | BRD-A97730597 | hexylcaine | SCN10A|SCN5A | sodium channel blocker | Details | |
| C02546 | BRD-A14234430 | hexylene-glycol | AKR1C3|CTPS1|DLG4|HSP90AA1|NOS3|PGF|PLA2G1B|PTPN1|SELP | Details | ||
| C02547 | BRD-K99946902 | hexylresorcinol | TYR | local anesthetic | Details | |
| C02548 | BRD-A55204514 | higenamine | ADRB2 | adrenergic receptor agonist | Details | |
| C02549 | BRD-K62914667 | hippuric-acid | Details | |||
| C02550 | BRD-K01674964 | histamine | HRH1|HRH2|HRH3|HRH4 | histamine receptor agonist | Details | |
| C02551 | BRD-K34411045 | HJC-0350 | RAPGEF4 | GTPase inhibitor | Details | |
| C02552 | BRD-K58811567 | HKI-357 | EGFR | EGFR inhibitor | Details | |
| C02553 | BRD-K73746696 | HLCL-61 | PRMT5 | protein arginine N-methyltransferase inhibitor | Details | |
| C02554 | BRD-K70511574 | HMN-214 | PLK1 | PLK inhibitor | Details | |
| C02555 | BRD-A74975734 | homatropine | CES1|CHRM1 | acetylcholine receptor antagonist | Details | |
| C02556 | BRD-A43999749 | homatropine-methylbromide | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor antagonist | Details | |
| C02557 | BRD-K28354016 | homidium | Details | |||
| C02558 | BRD-A22769835 | homochlorcyclizine | HRH1 | antihistamine | Details | |
| C02559 | BRD-K76674262 | homoharringtonine | RPL3 | protein synthesis inhibitor | Details | |
| C02560 | BRD-K30519779 | homoquinolinic-acid | GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D | glutamate receptor agonist | Details | |
| C02561 | BRD-A34751532 | homosalate | HSP inducer | Details | ||
| C02562 | BRD-K59570838 | homoveratrylamine | dopamine analog | Details | ||
| C02563 | BRD-K98493452 | honokiol | ALOX5|PTGS1|PTGS2 | AKT inhibitor | Details | |
| C02564 | BRD-K93631643 | hordenine | Details | |||
| C02565 | BRD-K44963273 | HQK-1001 | Details | |||
| C02566 | BRD-K58726989 | HTH-01-015 | NUAK1 | protein kinase inhibitor | Details | |
| C02567 | BRD-A66435872 | HTMT | HRH4 | histamine receptor agonist | Details | |
| C02568 | BRD-K62240499 | huperzine-a | ACHE | acetylcholinesterase inhibitor | Details | |
| C02569 | BRD-K59788572 | hyaluronic-acid | C1QBP|CD44|HABP2|HAPLN1|HAPLN3|HAPLN4|HMMR|ICAM1|NCAN|VCAN | Details | ||
| C02570 | BRD-K50406511 | hycanthone | RNA synthesis inhibitor | Details | ||
| C02571 | BRD-K82103381 | hydralazine | AOC3|P4HA1 | vasodilator | Details | |
| C02572 | BRD-K02715688 | hydrastine-(1r,-9s) | tyrosine hydroxylase inhibitor | Details | ||
| C02573 | BRD-A57900429 | hydrastinine | haemostatic agent | Details | ||
| C02574 | BRD-K13078532 | hydrochlorothiazide | CA1|CA12|CA2|CA4|CA9|KCNMA1|SLC12A3 | thiazide diuretic | Details | |
| C02575 | BRD-K93568044 | hydrocortisone | glucocorticoid receptor agonist | Details | ||
| C02576 | BRD-A65767837 | hydrocortisone-acetate | NR3C1|NR3C2 | glucocorticoid receptor agonist | Details | |
| C02577 | BRD-K99199077 | hydrocortisone-butyrate | NR3C1 | glucocorticoid receptor agonist | Details | |
| C02578 | BRD-A07000685 | hydrocortisone-hemisuccinate | Details | |||
| C02579 | BRD-A46186775 | hydrocortisone-phosphate | ANXA1|NOS2|NR3C1 | Details | ||
| C02580 | BRD-A25143711 | hydrocortisone-valerate | glucocorticoid receptor agonist | Details | ||
| C02581 | BRD-K36862742 | hydroflumethiazide | ATP1A1|CA1|CA12|CA2|CA4|CA9|KCNMA1|SLC12A1|SLC12A3 | sodium/potassium/chloride transporter inhibitor | Details | |
| C02582 | BRD-A06390036 | hydroquinidine | antiarrhythmic | Details | ||
| C02583 | BRD-K11227669 | hydroquinone | TYR | melanin inhibitor | Details | |
| C02584 | BRD-A80871782 | hydroxyamphetamine | TAAR1 | trace amine associated receptor agonist | Details | |
| C02585 | BRD-A99117172 | hydroxychloroquine | TLR7|TLR9 | antimalarial agent | Details | |
| C02586 | BRD-K77793136 | hydroxyfasudil | PKIA|PRKACA|ROCK1 | rho associated kinase inhibitor | Details | |
| C02587 | BRD-A39791822 | hydroxyprogesterone | PGR | progesterone receptor agonist | Details | |
| C02588 | BRD-K92902018 | hydroxyprogesterone-acetate | PGR | progesterone receptor agonist | Details | |
| C02589 | BRD-A01412266 | hydroxypropyl-beta-cyclodextrin | Details | |||
| C02590 | BRD-K62186992 | hydroxystilbamidine | Details | |||
| C02591 | BRD-A98299281 | hydroxytacrine-maleate-(r,s) | ACHE | cholinesterase inhibitor | Details | |
| C02592 | BRD-K75608666 | hydroxytoluic-acid | Details | |||
| C02593 | BRD-K51747290 | hydroxyurea | RRM1|RRM2|RRM2B | ribonucleotide reductase inhibitor | Details | |
| C02594 | BRD-A62428732 | hydroxyzine | HRH1 | antihistamine | Details | |
| C02595 | BRD-A67101513 | hygromycin-b | polypeptide synthesis inhibitor | Details | ||
| C02596 | BRD-K46424862 | hymecromone | MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C02597 | BRD-K44009692 | hyodeoxycholic-acid | atherosclerosis formation inhibitor | Details | ||
| C02598 | BRD-K40530731 | hyoscyamine | CHRM1|CHRM2|CHRM3|CHRM4 | acetylcholine receptor antagonist | Details | |
| C02599 | BRD-K29673530 | hypericin | tyrosine kinase inhibitor | Details | ||
| C02600 | BRD-A63780829 | hyperin | ACE|AKR1B1 | aldose reductase inhibitor | Details |