Repositioning Candidates
Repositioning candidates for CKD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and CKD-associated disease in CKDdb are presented with knowledge graphs.
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546 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0401 | DB01686 | experimental | small molecule | N,N-dimethylarginine | Details | |
| R0402 | DB01708 | approved; investigational; nutraceutical | small molecule | Prasterone | Details | |
| R0403 | DB01783 | approved; nutraceutical; vet_approved | small molecule | Pantothenic acid | Details | |
| R0404 | DB01956 | approved; nutraceutical | small molecule | Taurine | Details | |
| R0405 | DB02300 | approved | small molecule | Calcipotriol | Details | |
| R0406 | DB02513 | approved | small molecule | Thymol | Details | |
| R0407 | DB02530 | approved; investigational | small molecule | gamma-Aminobutyric acid | Details | |
| R0408 | DB02638 | approved; investigational | small molecule | Terlipressin | Details | |
| R0409 | DB02701 | approved; investigational | small molecule | Nicotinamide | Details | |
| R0410 | DB02703 | approved; investigational | small molecule | Fusidic acid | Details | |
| R0411 | DB02709 | approved; experimental; investigational | small molecule | Resveratrol | Details | |
| R0412 | DB02959 | approved; investigational; nutraceutical | small molecule | Oxitriptan | Details | |
| R0413 | DB03085 | approved; investigational | small molecule | Glycolic acid | Details | |
| R0414 | DB03128 | approved; investigational | small molecule | Acetylcholine | Details | |
| R0415 | DB03166 | approved | small molecule | Acetic acid | Details | |
| R0416 | DB03255 | approved; experimental | small molecule | Phenol | Details | |
| R0417 | DB03796 | approved | small molecule | Palmitic Acid | Details | |
| R0418 | DB03852 | experimental; nutraceutical | small molecule | Eucalyptol | Details | |
| R0419 | DB04272 | approved; nutraceutical; vet_approved | small molecule | Citric acid | Details | |
| R0420 | DB04299 | experimental | small molecule | Maleic Acid | Details | |
| R0421 | DB04455 | experimental; investigational | small molecule | N,N,N-trimethylglycinium | Details | |
| R0422 | DB04481 | experimental | small molecule | Meso-Erythritol | Details | |
| R0423 | DB04532 | experimental | small molecule | Indole | Details | |
| R0424 | DB04557 | experimental | small molecule | Arachidonic Acid | Details | |
| R0425 | DB04830 | investigational; withdrawn | small molecule | Buformin | Details | |
| R0426 | DB04833 | illicit; withdrawn | small molecule | Methaqualone | Details | |
| R0427 | DB04839 | approved; investigational | small molecule | Cyproterone acetate | Details | |
| R0428 | DB04842 | approved; investigational | small molecule | Fluspirilene | Details | |
| R0429 | DB04844 | approved; investigational | small molecule | Tetrabenazine | Details | |
| R0430 | DB04854 | approved | small molecule | Febuxostat | Details | |
| R0431 | DB04861 | approved; investigational | small molecule | Nebivolol | Details | |
| R0432 | DB04876 | approved; investigational | small molecule | Vildagliptin | Details | |
| R0433 | DB04878 | investigational | small molecule | Voglibose | Details | |
| R0434 | DB04946 | approved | small molecule | Iloperidone | Details | |
| R0435 | DB05137 | investigational | small molecule | Lobeline | Details | |
| R0436 | DB05381 | approved; investigational | small molecule | Histamine | Details | |
| R0437 | DB05382 | approved; investigational | small molecule | Iodine | Details | |
| R0438 | DB05667 | investigational | small molecule | Levoketoconazole | Details | |
| R0439 | DB06151 | approved; investigational | small molecule | Acetylcysteine | Details | |
| R0440 | DB06199 | investigational | small molecule | Atrasentan | Details | |
| R0441 | DB06228 | approved | small molecule | Rivaroxaban | Details | |
| R0442 | DB06243 | approved; withdrawn | small molecule | Eflornithine | Details | |
| R0443 | DB06268 | approved; investigational; withdrawn | small molecule | Sitaxentan | Details | |
| R0444 | DB06288 | approved; investigational | small molecule | Amisulpride | Details | |
| R0445 | DB06292 | approved | small molecule | Dapagliflozin | Details | |
| R0446 | DB06311 | investigational | small molecule | Darapladib | Details | |
| R0447 | DB06335 | approved | small molecule | Saxagliptin | Details | |
| R0448 | DB06403 | approved; investigational | small molecule | Ambrisentan | Details | |
| R0449 | DB06414 | approved | small molecule | Etravirine | Details | |
| R0450 | DB06480 | approved | small molecule | Prucalopride | Details | |
| R0451 | DB06586 | investigational | small molecule | Cetilistat | Details | |
| R0452 | DB06594 | approved; investigational | small molecule | Agomelatine | Details | |
| R0453 | DB06605 | approved | small molecule | Apixaban | Details | |
| R0454 | DB06616 | approved | small molecule | Bosutinib | Details | |
| R0455 | DB06700 | approved; investigational | small molecule | Desvenlafaxine | Details | |
| R0456 | DB06710 | approved | small molecule | Methyltestosterone | Details | |
| R0457 | DB06755 | approved; nutraceutical | small molecule | Beta carotene | Details | |
| R0458 | DB06757 | approved; nutraceutical | small molecule | Manganese | Details | |
| R0459 | DB06774 | approved | small molecule | Capsaicin | Details | |
| R0460 | DB06777 | approved | small molecule | Chenodeoxycholic acid | Details | |
| R0461 | DB06778 | approved | small molecule | Cupric sulfate | Details | |
| R0462 | DB06791 | approved | small molecule | Lanreotide | Details | |
| R0463 | DB06809 | approved | small molecule | Plerixafor | Details | |
| R0464 | DB06819 | approved; investigational | small molecule | Phenylbutyric acid | Details | |
| R0465 | DB06973 | experimental | small molecule | 4,4'-PROPANE-2,2-DIYLDIPHENOL | Details | |
| R0466 | DB07715 | investigational | small molecule | Emodin | Details | |
| R0467 | DB07919 | experimental | small molecule | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE | Details | |
| R0468 | DB08439 | approved | small molecule | Parecoxib | Details | |
| R0469 | DB08604 | approved; investigational | small molecule | Triclosan | Details | |
| R0470 | DB08804 | approved; illicit | small molecule | Nandrolone decanoate | Details | |
| R0471 | DB08816 | approved | small molecule | Ticagrelor | Details | |
| R0472 | DB08826 | approved | small molecule | Deferiprone | Details | |
| R0473 | DB08844 | investigational | small molecule | Uric acid | Details | |
| R0474 | DB08860 | approved | small molecule | Pitavastatin | Details | |
| R0475 | DB08864 | approved | small molecule | Rilpivirine | Details | |
| R0476 | DB08890 | approved | small molecule | Linaclotide | Details | |
| R0477 | DB08895 | approved; investigational | small molecule | Tofacitinib | Details | |
| R0478 | DB08908 | approved; investigational | small molecule | Dimethyl fumarate | Details | |
| R0479 | DB08934 | approved | small molecule | Sofosbuvir | Details | |
| R0480 | DB08997 | withdrawn | small molecule | Dexetimide | Details | |
| R0481 | DB09020 | approved | small molecule | Bisacodyl | Details | |
| R0482 | DB09026 | approved; investigational | small molecule | Aliskiren | Details | |
| R0483 | DB09027 | approved | small molecule | Ledipasvir | Details | |
| R0484 | DB09055 | approved; investigational | small molecule | Acipimox | Details | |
| R0485 | DB09064 | approved; investigational | small molecule | Ciprofibrate | Details | |
| R0486 | DB09074 | approved | small molecule | Olaparib | Details | |
| R0487 | DB09096 | approved | small molecule | Benzoyl peroxide | Details | |
| R0488 | DB09110 | approved; investigational | small molecule | Coenzyme M | Details | |
| R0489 | DB09220 | approved; investigational | small molecule | Nicorandil | Details | |
| R0490 | DB09238 | approved; investigational | small molecule | Manidipine | Details | |
| R0491 | DB09241 | approved; investigational | small molecule | Methylene blue | Details | |
| R0492 | DB09242 | approved; investigational | small molecule | Moxonidine | Details | |
| R0493 | DB09270 | approved; investigational; nutraceutical | small molecule | Ubidecarenone | Details | |
| R0494 | DB09298 | experimental; investigational | small molecule | Silibinin | Details | |
| R0495 | DB09462 | approved; investigational | small molecule | Glycerin | Details | |
| R0496 | DB09543 | approved; vet_approved | small molecule | Methyl salicylate | Details | |
| R0497 | DB09570 | approved; investigational | small molecule | Ixazomib | Details | |
| R0498 | DB11091 | approved; vet_approved | small molecule | Hydrogen peroxide | Details | |
| R0499 | DB11231 | approved; investigational | small molecule | Lycopene | Details | |
| R0500 | DB11428 | experimental; vet_approved | small molecule | Medetomidine | Details |