CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C01001 | BRD-K26530649 | carboxypyridine-disulfide | Details | |||
| C01002 | BRD-K99174507 | cardiogenol-c | cardiomyogenesis inducer | Details | ||
| C01003 | BRD-K50905564 | cardionogen-1 | CTNNB1 | WNT signaling inhibitor | Details | |
| C01004 | BRD-K49554218 | carebastine | HRH1 | histamine receptor antagonist | Details | |
| C01005 | BRD-K15179879 | carfilzomib | PSMA1|PSMA2|PSMA3|PSMA4|PSMA5|PSMA6|PSMA7|PSMA8|PSMB1|PSMB10|PSMB11|PSMB2|PSMB3|PSMB4|PSMB5|PSMB6|PSMB7|PSMB8|PSMB9 | proteasome inhibitor | Details | |
| C01006 | BRD-K60240222 | carglumic-acid | CPS1 | carbamoyl phosphate synthase activator | Details | |
| C01007 | BRD-K90215590 | caricotamide | NQO2 | NADPH quinone oxidoreductase inhibitor | Details | |
| C01008 | BRD-K21670884 | cariporide | SLC9A1 | sodium/hydrogen exchanger inhibitor | Details | |
| C01009 | BRD-K57764956 | cariprazine | DRD2|DRD3 | dopamine receptor antagonist | Details | |
| C01010 | BRD-A99939097 | carisoprodol | CYP2C19 | acetylcholine receptor antagonist | Details | |
| C01011 | BRD-K11630072 | carmofur | TYMS | thymidylate synthase inhibitor | Details | |
| C01012 | BRD-K25095405 | carmoterol | ADRB2 | adrenergic receptor agonist | Details | |
| C01013 | BRD-K82484965 | carmoxirole | DRD2 | dopamine receptor agonist | Details | |
| C01014 | BRD-K36234266 | carmustine | GSR | DNA alkylating agent; DNA inhibitor | Details | |
| C01015 | BRD-A89594340 | carnitine-(D/L) | Details | |||
| C01016 | BRD-A96051074 | carnosine | antiglycating agent | Details | ||
| C01017 | BRD-K65900713 | caroverine | glutamate receptor antagonist; calcium channel blocker | Details | ||
| C01018 | BRD-K92129045 | caroxazone | MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C01019 | BRD-A17411484 | carprofen | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C01020 | BRD-K13238618 | carsalam | analgesic agent | Details | ||
| C01021 | BRD-A42167015 | carteolol | ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C01022 | BRD-K71026158 | carumonam | bacterial cell wall synthesis inhibitor | Details | ||
| C01023 | BRD-A10977446 | carvedilol | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|ADRB1|ADRB2|ADRB3|GJA1|HIF1A|KCNH2|NDUFC2|NPPB|SELE|VCAM1|VEGFA | adrenergic receptor antagonist | Details | |
| C01024 | BRD-K09295674 | carzenide | CA1|CA12|CA14|CA2|CA6|CA9 | Details | ||
| C01025 | BRD-K12413266 | casanthranol-variant | Details | |||
| C01026 | BRD-A25043798 | casin | CDC42 | GTPase inhibitor | Details | |
| C01027 | BRD-A31685486 | caspofungin | fungal 1,3-beta-D-glucan synthase inhibitor; bacterial cell wall synthesis inhibitor | Details | ||
| C01028 | BRD-K49793107 | caspofungin-acetate | fungal 1,3-beta-D-glucan synthase inhibitor | Details | ||
| C01029 | BRD-K20897876 | castanospermine | GAA|GBA | glucosidase inhibitor | Details | |
| C01030 | BRD-K92377961 | catharanthine | tubulin polymerization inhibitor | Details | ||
| C01031 | BRD-K40269473 | cathepsin-inhibitor-1 | CTSB|CTSL|CTSV | cathepsin inhibitor | Details | |
| C01032 | BRD-K40366680 | CAY10505 | PIK3CG | PI3K inhibitor | Details | |
| C01033 | BRD-K41779183 | CB-03-01 | AR | androgen receptor antagonist | Details | |
| C01034 | BRD-K59929863 | CB-10-277 | DNA synthesis inhibitor | Details | ||
| C01035 | BRD-K49048664 | CB-5083 | VCP | valosin-containing protein inhibitor | Details | |
| C01036 | BRD-K58070273 | CB-839 | GLS | glutaminase inhibitor | Details | |
| C01037 | BRD-K34675210 | CBiPES | GRM2 | glutamate receptor positive allosteric modulator | Details | |
| C01038 | BRD-K64191834 | CBS,-N-Cyclohexyl-2-benzothiazolesulfenamide | Details | |||
| C01039 | BRD-K91874254 | CBS-1114 | ALOX5 | lipoxygenase inhibitor | Details | |
| C01040 | BRD-K16755045 | CC-115 | MTOR | mTOR inhibitor; DNA protein kinase inhibitor | Details | |
| C01041 | BRD-K88737571 | CC-223 | MTOR | mTOR inhibitor | Details | |
| C01042 | BRD-K45746021 | CC-401 | MAPK8 | JNK inhibitor | Details | |
| C01043 | BRD-K48213016 | CC-930 | JNK inhibitor | Details | ||
| C01044 | BRD-A79726147 | CCG-1423 | RHOC|SRF | apoptosis stimulant | Details | |
| C01045 | BRD-K08893438 | CCG-50014 | RGS4|RGS8 | G protein signaling inhibitor | Details | |
| C01046 | BRD-K26970495 | CCG-63802 | RGS4 | G protein signaling inhibitor | Details | |
| C01047 | BRD-K68474505 | CCG-63808 | RGS4 | G protein signaling inhibitor | Details | |
| C01048 | BRD-K16338837 | CCMI | CHRNA7 | acetylcholine receptor allosteric modulator | Details | |
| C01049 | BRD-K06159959 | CCMQ | homoquinolinic acid binding inhibitor | Details | ||
| C01050 | BRD-K90999434 | CCT-031374 | CTNNB1 | WNT signaling inhibitor | Details | |
| C01051 | BRD-K65503129 | CCT018159 | HSP90AA1|HSP90AB1 | HSP inhibitor | Details | |
| C01052 | BRD-K76406695 | CCT128930 | PKIA|PRKACA | AKT inhibitor | Details | |
| C01053 | BRD-K57136142 | CCT129202 | AURKA|AURKB|AURKC | Aurora kinase inhibitor | Details | |
| C01054 | BRD-K03289018 | CCT137690 | AURKA|AURKB|AURKC | Aurora kinase inhibitor | Details | |
| C01055 | BRD-K17751100 | CC4 | CHRNB2 | nicotinic receptor agonist | Details | |
| C01056 | BRD-K09619322 | CD-1530 | RARG | retinoid receptor agonist | Details | |
| C01057 | BRD-K28907958 | CD-437 | RARG | retinoid receptor agonist | Details | |
| C01058 | BRD-A08079565 | CDBA | Details | |||
| C01059 | BRD-K87932577 | CDK1-5-inhibitor | CDK1|CDK5|GSK3B | CDK inhibitor; glycogen synthase kinase inhibitor | Details | |
| C01060 | BRD-K43914553 | CDK9-IN-6 | CDK9 | CDK inhibitor | Details | |
| C01061 | BRD-K02213468 | CDPPB | GRM5 | glutamate receptor positive allosteric modulator | Details | |
| C01062 | BRD-K48141473 | cebranopadol | OPRL1|OPRM1 | opioid receptor agonist | Details | |
| C01063 | BRD-K86930074 | cediranib | CSF1R|FLT1|FLT3|FLT4|KDR|KIT|PDGFRA|PDGFRB | KIT inhibitor; VEGFR inhibitor | Details | |
| C01064 | BRD-A61188230 | cedrol | Details | |||
| C01065 | BRD-K96362839 | cedrol-(+) | sedative | Details | ||
| C01066 | BRD-K20338176 | cefaclor | bacterial cell wall synthesis inhibitor | Details | ||
| C01067 | BRD-A56858165 | cefadroxil | SLC15A1|SLC15A2|SLC22A6|SLC22A8 | bacterial cell wall synthesis inhibitor | Details | |
| C01068 | BRD-K15514357 | cefalonium | bacterial cell wall synthesis inhibitor | Details | ||
| C01069 | BRD-K27130738 | cefamandole | bacterial cell wall synthesis inhibitor | Details | ||
| C01070 | BRD-K17903788 | cefamandole-nafate | bacterial cell wall synthesis inhibitor | Details | ||
| C01071 | BRD-K63835048 | cefathiamidine | bacterial cell wall synthesis inhibitor | Details | ||
| C01072 | BRD-K99750640 | cefazolin | PON1 | bacterial cell wall synthesis inhibitor | Details | |
| C01073 | BRD-K27515606 | cefcapene-pivoxil | bacterial cell wall synthesis inhibitor | Details | ||
| C01074 | BRD-K15766189 | cefdinir | MPO | bacterial cell wall synthesis inhibitor | Details | |
| C01075 | BRD-K72167406 | cefditoren-pivoxil | bacterial cell wall synthesis inhibitor | Details | ||
| C01076 | BRD-A12077521 | cefepime | bacterial cell wall synthesis inhibitor | Details | ||
| C01077 | BRD-K27798832 | cefetamet | bacterial cell wall synthesis inhibitor | Details | ||
| C01078 | BRD-K21372554 | cefetamet-pivoxil | bacterial cell wall synthesis inhibitor | Details | ||
| C01079 | BRD-K71059170 | cefixime | bacterial cell wall synthesis inhibitor | Details | ||
| C01080 | BRD-A20839672 | cefmenoxime | bacterial cell wall synthesis inhibitor | Details | ||
| C01081 | BRD-K48470486 | cefmetazole | bacterial cell wall synthesis inhibitor | Details | ||
| C01082 | BRD-K77073709 | cefminox | bacterial cell wall synthesis inhibitor | Details | ||
| C01083 | BRD-K22641081 | cefodizime | bacterial cell wall synthesis inhibitor | Details | ||
| C01084 | BRD-K34058848 | cefonicid | bacterial cell wall synthesis inhibitor | Details | ||
| C01085 | BRD-K02292852 | cefoperazone | bacterial cell wall synthesis inhibitor | Details | ||
| C01086 | BRD-K37848908 | ceforanide | penicillin binding protein inhibitor | Details | ||
| C01087 | BRD-K72339976 | cefoselis | bacterial cell wall synthesis inhibitor | Details | ||
| C01088 | BRD-K78364995 | cefotaxime | bacterial cell wall synthesis inhibitor | Details | ||
| C01089 | BRD-A78723049 | cefotetan | bacterial cell wall synthesis inhibitor | Details | ||
| C01090 | BRD-K02275692 | cefotiam | bacterial cell wall synthesis inhibitor | Details | ||
| C01091 | BRD-A76661185 | cefotiam-cilexetil | bacterial cell wall synthesis inhibitor | Details | ||
| C01092 | BRD-K70976396 | cefoxitin | bacterial cell wall synthesis inhibitor | Details | ||
| C01093 | BRD-K46970505 | cefozopran | bacterial cell wall synthesis inhibitor | Details | ||
| C01094 | BRD-K92872987 | cefpiramide | bacterial cell wall synthesis inhibitor | Details | ||
| C01095 | BRD-K56542719 | cefpirome | bacterial cell wall synthesis inhibitor | Details | ||
| C01096 | BRD-A34205213 | cefpodoxime | bacterial cell wall synthesis inhibitor | Details | ||
| C01097 | BRD-K24871708 | cefprozil | bacterial cell wall synthesis inhibitor | Details | ||
| C01098 | BRD-K13797099 | cefradine | CYP3A4 | bacterial cell wall synthesis inhibitor | Details | |
| C01099 | BRD-K03907181 | cefsulodin | bacterial cell wall synthesis inhibitor | Details | ||
| C01100 | BRD-K37252028 | ceftaroline-fosamil | bacterial cell wall synthesis inhibitor | Details |