CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
stats1
stats2
6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C04901 | BRD-A53504839 | sennoside-protonated | Details | |||
| C04902 | BRD-K28456624 | seocalcitol | VDR | vitamin D receptor agonist | Details | |
| C04903 | BRD-K49504902 | SEP-227900 | DAO | D-Amino Acid Oxidase Inhibitor | Details | |
| C04904 | BRD-A60765580 | seratrodast | TBXA2R | prostanoid receptor antagonist | Details | |
| C04905 | BRD-K65924316 | serdemetan | MDM2 | MDM inhibitor | Details | |
| C04906 | BRD-K38580127 | serotonin | DRD1|DRD5|HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR3A|HTR3B|HTR4|HTR5A|HTR6|HTR7|SLC36A1 | growth factor receptor activator | Details | |
| C04907 | BRD-A95939040 | sertaconazole | sterol demethylase inhibitor | Details | ||
| C04908 | BRD-K69116396 | sertindole | ADRA1A|ADRA1B|ADRA1D|DRD2|DRD3|DRD4|HRH1|HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2C|HTR6|KCNH2 | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C04909 | BRD-K82036761 | sertraline | SLC6A3|SLC6A4 | selective serotonin reuptake inhibitor (SSRI) | Details | |
| C04910 | BRD-K11631773 | sesamin | NFkB pathway inhibitor | Details | ||
| C04911 | BRD-K24497734 | setipiprant | PTGDR2 | prostaglandin inhibitor | Details | |
| C04912 | BRD-K36732695 | setiptiline | HRH1|HTR2A|HTR2C | adrenergic receptor antagonist | Details | |
| C04913 | BRD-U45393375 | sevelamer | phosphate antagonist | Details | ||
| C04914 | BRD-K05638300 | sevoflurane | ATP2C1|ATP5D|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GLRA1|GLRB|GRIA1|KCNA1|KCNK10|KCNK18|KCNK2|KCNK3|KCNK9|MT-ND1 | membrane integrity inhibitor | Details | |
| C04915 | BRD-K15601958 | SEW-2871 | S1PR1 | lysophospholipid receptor agonist | Details | |
| C04916 | BRD-K42629487 | SF-11 | MCOLN3|NPY2R | neuropeptide receptor antagonist | Details | |
| C04917 | BRD-K24821794 | SGC-CBP30 | CREBBP|EP300 | bromodomain inhibitor | Details | |
| C04918 | BRD-K69577666 | SGC-0946 | histone lysine methyltransferase inhibitor | Details | ||
| C04919 | BRD-K86718786 | SGC-707 | PRMT3 | protein arginine N-methyltransferase inhibitor | Details | |
| C04920 | BRD-K61228301 | SGI-1027 | DNMT1|DNMT3A|DNMT3B | DNA methyltransferase inhibitor | Details | |
| C04921 | BRD-K80700417 | SGI-1776 | FLT3|PIM1|PIM2|PIM3 | Pim kinase inhibitor | Details | |
| C04922 | BRD-K19477839 | SGX523 | MET | hepatocyte growth factor receptor inhibitor | Details | |
| C04923 | BRD-A63344375 | SHA-68 | NPSR1 | neuropeptide receptor antagonist | Details | |
| C04924 | BRD-A92096630 | shikimic-acid | Details | |||
| C04925 | BRD-K00818915 | SHP099 | PTPN11 | protein tyrosine kinase inhibitor | Details | |
| C04926 | BRD-A79052425 | SIB-1553A | CHRNB4 | acetylcholine receptor agonist | Details | |
| C04927 | BRD-K98157055 | SIB-1757 | GRM5 | glutamate receptor antagonist | Details | |
| C04928 | BRD-K14561059 | SIB-1893 | GRM4|GRM5 | glutamate receptor antagonist | Details | |
| C04929 | BRD-A23359898 | sibutramine | SLC6A2|SLC6A3|SLC6A4 | serotonin norepinephrine reuptake inhibitor (SNRI) | Details | |
| C04930 | BRD-A43885598 | SID-7969543 | NR5A1 | steroidogenic factor antagonist | Details | |
| C04931 | BRD-A62071884 | siguazodan | PDE3A | phosphodiesterase inhibitor | Details | |
| C04932 | BRD-K79759585 | sildenafil | PDE5A|PDE6G|PDE6H|SLCO1B1|SLCO1B3 | phosphodiesterase inhibitor | Details | |
| C04933 | BRD-K80353138 | silibinin | ALOX5 | cytochrome P450 inhibitor | Details | |
| C04934 | BRD-K10906636 | silodosin | ADRA1A|ADRA1B|ADRA1D | adrenergic receptor antagonist | Details | |
| C04935 | BRD-K68379918 | silver-sulfadiazine | PABA antagonist | Details | ||
| C04936 | BRD-A06629414 | silymarin | Details | |||
| C04937 | BRD-A68493689 | simeprevir | CYP1A2|CYP3A4 | HCV inhibitor | Details | |
| C04938 | BRD-K22134346 | simvastatin | HMGCR|ITGB2 | HMGCR inhibitor | Details | |
| C04939 | BRD-K91100918 | sinefungin | CARM1 | DNA methyltransferase inhibitor; RNA synthesis inhibitor | Details | |
| C04940 | BRD-K83459933 | sinomenine | angiogenesis inhibitor | Details | ||
| C04941 | BRD-K53195974 | sipatrigine | CACNA1D|SCN10A|SCN1A|SCN3A|SCN4A|SCN5A|SCN9A | voltage-gated sodium channel blocker | Details | |
| C04942 | BRD-K62384160 | siponimod | S1PR1 | sphingosine phosphate receptor modulator | Details | |
| C04943 | BRD-K51333959 | siramesine | ADRA1A|ADRA1B|ADRA1D | sigma receptor antagonist | Details | |
| C04944 | BRD-K84937637 | sirolimus | FGF2|FKBP1A|MTOR | mTOR inhibitor | Details | |
| C04945 | BRD-K16472653 | SirReal-2 | SIRT2 | SIRT inhibitor | Details | |
| C04946 | BRD-A23747351 | sirtinol | SIRT1|SIRT2 | SIRT inhibitor | Details | |
| C04947 | BRD-K71772032 | sisomicin | protein synthesis inhibitor | Details | ||
| C04948 | BRD-A68997559 | sisomicin-sulfate | bacterial 30S ribosomal subunit inhibitor | Details | ||
| C04949 | BRD-K38905597 | SIS3 | SMAD3|TGFBR1 | serine/threonine kinase inhibitor | Details | |
| C04950 | BRD-K10836013 | sitafloxacin | bacterial DNA gyrase inhibitor | Details | ||
| C04951 | BRD-K19416115 | sitagliptin | DPP4 | dipeptidyl peptidase inhibitor | Details | |
| C04952 | BRD-K63806092 | sitaxentan | EDNRA | endothelin receptor antagonist | Details | |
| C04953 | BRD-K79402892 | sitosterol | Details | |||
| C04954 | BRD-K02152879 | sivelestat | CELA1|ELANE | elastase inhibitor | Details | |
| C04955 | BRD-K35945299 | SJ-172550 | MDM4 | MDM inhibitor | Details | |
| C04956 | BRD-A47364545 | SK&F-10047-(+) | SIGMAR1 | sigma receptor agonist | Details | |
| C04957 | BRD-K67304264 | SKA-31 | KCNN4 | potassium channel activator | Details | |
| C04958 | BRD-K83607951 | skepinone-l | MAPK14 | p38 MAPK inhibitor | Details | |
| C04959 | BRD-A88548664 | SKF-38393 | CALY|DRD1|DRD5 | dopamine receptor agonist | Details | |
| C04960 | BRD-A64227845 | SKF-77434 | DRD1 | dopamine receptor agonist | Details | |
| C04961 | BRD-A09828896 | SKF-81297 | DRD1|DRD5 | dopamine receptor agonist | Details | |
| C04962 | BRD-A52588987 | SKF-83566 | DRD1|DRD5 | dopamine receptor antagonist | Details | |
| C04963 | BRD-K96809896 | SKF-86002 | ALOX5|MAPK14 | p38 MAPK inhibitor | Details | |
| C04964 | BRD-A49046702 | SKF-89976A | SLC6A1 | GABA uptake inhibitor | Details | |
| C04965 | BRD-K49776472 | SKF-91488 | HNMT | histamine N-methyltransferase inhibitor | Details | |
| C04966 | BRD-A72703248 | SKF-96365 | CYP3A4|PKD2|TRPC1|TRPC3|TRPC4|TRPC5|TRPV2 | calcium channel blocker | Details | |
| C04967 | BRD-K20755323 | SKI-II | SPHK1 | sphingosine kinase inhibitor | Details | |
| C04968 | BRD-K29895144 | SKLB1002 | KDR | VEGFR inhibitor | Details | |
| C04969 | BRD-A54228901 | SLV-319-(+/-) | CNR1|DRD2|HTR1A | cannabinoid receptor antagonist | Details | |
| C04970 | BRD-K34445261 | SLV-320 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C04971 | BRD-K70053378 | SM-108 | Details | |||
| C04972 | BRD-K06191411 | SM-164 | BIRC2|BIRC3|XIAP | XIAP inhibitor | Details | |
| C04973 | BRD-A92933783 | SM-21 | PGRMC1 | sigma receptor antagonist | Details | |
| C04974 | BRD-K08478539 | SMER-28 | SNCA | autophagy inducer | Details | |
| C04975 | BRD-K70159787 | SMI-4a | PIM1 | Pim kinase inhibitor | Details | |
| C04976 | BRD-A64319165 | SN-2 | MCOLN3 | transient receptor potential channel agonist | Details | |
| C04977 | BRD-K89561498 | SN-38 | TOP1 | topoisomerase inhibitor | Details | |
| C04978 | BRD-A14316475 | SN-6 | sodium/calcium exchange inhibitor | Details | ||
| C04979 | BRD-A67006024 | SNAP | PTPN1 | nitric oxide donor | Details | |
| C04980 | BRD-A21428877 | SNAP-5089 | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|CACNA1C|CACNA1D | adrenergic receptor antagonist | Details | |
| C04981 | BRD-K49702221 | SNAP-94847 | ADRA1A|DRD2 | Details | ||
| C04982 | BRD-K29546239 | SNC-80 | OPRD1 | Details | ||
| C04983 | BRD-K75016267 | SNG-1153 | ESR1 | selective estrogen receptor modulator (SERM) | Details | |
| C04984 | BRD-K71512533 | SNS-314 | AURKA|AURKB|AURKC | Aurora kinase inhibitor | Details | |
| C04985 | BRD-K71281111 | SNX-2112 | HSP inhibitor | Details | ||
| C04986 | BRD-K73197500 | SNX-5422 | HSP90AA1 | HSP inhibitor | Details | |
| C04987 | BRD-K85406984 | sobetirome | THRA|THRB | thyroid hormone receptor agonist | Details | |
| C04988 | BRD-K58262380 | sobrepin | mucolytic agent | Details | ||
| C04989 | BRD-A67265925 | sodium-ascorbate | Details | |||
| C04990 | BRD-K05878375 | sodium-butyrate | BCHE|FFAR2|FFAR3|HDAC1|HDAC2|HDAC3|HDAC8 | HDAC inhibitor | Details | |
| C04991 | BRD-A93699261 | sodium-danshensu | Details | |||
| C04992 | BRD-M58433298 | sodium-dodecyl-sulfate | ALB|LYZ | Details | ||
| C04993 | BRD-K35952844 | sodium-glucoheptonate | Details | |||
| C04994 | BRD-K93201765 | sodium-gluconate | Details | |||
| C04995 | BRD-K80043866 | sodium-gualenate | antacid | Details | ||
| C04996 | BRD-K99308954 | sodium-monofluorophosphate | PYGM | Details | ||
| C04997 | BRD-K61230716 | sodium-nitrite | nitric oxide donor | Details | ||
| C04998 | BRD-K48526231 | sodium-nitroprusside | nitric oxide donor | Details | ||
| C04999 | BRD-K60600693 | sodium-orthovanadate | Details | |||
| C05000 | BRD-K82166906 | sodium-oxybate | GABRB1|HCAR1|SLC52A2 | benzodiazepine receptor agonist | Details |