CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
stats1
stats2
6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00701 | BRD-M02899238 | beta-hydroxy-beta-methylbutyrate | MTOR | protein synthesis stimulant | Details | |
| C00702 | BRD-A41387824 | beta-Hydroxybutyrate | HCAR2 | Details | ||
| C00703 | BRD-K28061410 | beta-lapachone | TOP1 | topoisomerase inhibitor | Details | |
| C00704 | BRD-K21164796 | beta-naphthol | Details | |||
| C00705 | BRD-K91315211 | betahistine | HRH1|HRH3 | histamine receptor agonist; histamine receptor antagonist | Details | |
| C00706 | BRD-K12014493 | betaine | nitric oxide donor | Details | ||
| C00707 | BRD-A02180903 | betamethasone | NR3C1 | glucocorticoid receptor agonist | Details | |
| C00708 | BRD-A92177080 | betamethasone-acetate | NR3C1 | glucocorticoid receptor agonist | Details | |
| C00709 | BRD-K58148589 | betamethasone-dipropionate | anti-inflammatory agent | Details | ||
| C00710 | BRD-K34032314 | betamethasone-valerate | NR3C1 | glucocorticoid receptor agonist | Details | |
| C00711 | BRD-K82142815 | betamipron | panipenem uptake inhibitor | Details | ||
| C00712 | BRD-A02759312 | betaxolol | ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C00713 | BRD-K20075662 | betazole | HRH2 | histamine receptor agonist | Details | |
| C00714 | BRD-A99833829 | bethanechol | CHRM1|CHRM2|CHRM3|CHRM4 | acetylcholine receptor agonist | Details | |
| C00715 | BRD-A60153876 | BETP | GLP1R | glucagon-like peptide receptor positive allosteric modulator | Details | |
| C00716 | BRD-K45275534 | betrixaban | KCNH2 | coagulation factor inhibitor | Details | |
| C00717 | BRD-K45401373 | betulinic-acid | GPBAR1 | apoptosis stimulant; NFkB pathway inhibitor | Details | |
| C00718 | BRD-A18233884 | bevantolol | ADRA1A|ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C00719 | BRD-K16898998 | bevirimat-dimeglumine | HIV capsid assembly inhibitor | Details | ||
| C00720 | BRD-K92441787 | bexarotene | RXRA|RXRB|RXRG | retinoid receptor agonist | Details | |
| C00721 | BRD-K46018455 | bezafibrate | PPARA|PPARD|PPARG | PPAR receptor agonist | Details | |
| C00722 | BRD-K21673112 | BF2.649 | HRH3 | histamine receptor antagonist | Details | |
| C00723 | BRD-K29415052 | BGT226 | MTOR|PIK3CA|PIK3CB|PIK3CG | PI3K inhibitor | Details | |
| C00724 | BRD-K95603879 | BHQ | ATP2A1 | ATPase inhibitor | Details | |
| C00725 | BRD-A81370665 | BI-D1870 | RPS6KA1|RPS6KA2|RPS6KA3|RPS6KA6 | ribosomal protein inhibitor | Details | |
| C00726 | BRD-K53422148 | BI-224436 | HIV integrase inhibitor | Details | ||
| C00727 | BRD-K64890080 | BI-2536 | BRD4|PLK1|PLK2|PLK3 | PLK inhibitor | Details | |
| C00728 | BRD-K73982490 | BI-78D3 | MAPK8 | JNK inhibitor | Details | |
| C00729 | BRD-K37492701 | BI-847325 | AURKA|AURKB|AURKC|MAP2K1|MAP2K2 | MEK inhibitor; Aurora kinase inhibitor | Details | |
| C00730 | BRD-A80321291 | biapenem | bacterial cell wall synthesis inhibitor | Details | ||
| C00731 | BRD-K43927145 | BIBN4096 | CALCA|CALCRL|RAMP1 | calcitonin antagonist | Details | |
| C00732 | BRD-K04623885 | BIBR-1532 | TERT | telomerase inhibitor | Details | |
| C00733 | BRD-K49294207 | BIBU-1361 | EGFR | EGFR inhibitor | Details | |
| C00734 | BRD-K70914287 | BIBX-1382 | EGFR|ERBB2 | EGFR inhibitor | Details | |
| C00735 | BRD-A29485665 | bicalutamide | AR | androgen receptor antagonist | Details | |
| C00736 | BRD-A24208517 | bicifadine | DRD2|SLC6A2|SLC6A4 | serotonin receptor antagonist; dopamine reuptake inhibitor | Details | |
| C00737 | BRD-A07870296 | bicuculline-(+) | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|KCNN1 | GABA receptor antagonist | Details | |
| C00738 | BRD-A57798559 | bicuculline-methochloride-(-) | GABA receptor antagonist | Details | ||
| C00739 | BRD-K16546375 | bicyclol | HSPA1A|HSPB1 | NFkB pathway inhibitor | Details | |
| C00740 | BRD-K18779551 | bifemelane | MAOA|MAOB | acetylcholine release enhancer | Details | |
| C00741 | BRD-K26581543 | bifendate | Details | |||
| C00742 | BRD-A94543220 | bifonazole | CYP2B6 | sterol demethylase inhibitor | Details | |
| C00743 | BRD-K51967704 | BIIB021 | HSP90AA1 | HSP inhibitor | Details | |
| C00744 | BRD-K51937257 | bilastine | HRH1 | histamine receptor antagonist | Details | |
| C00745 | BRD-A41714661 | bilobalide | GLRA1|GLRA2|GLRB|HTR3A|HTR3B | GABA receptor modulator | Details | |
| C00746 | BRD-A45153512 | bimatoprost | AKR1C3|PTGER1|PTGER3|PTGFR | prostanoid receptor agonist | Details | |
| C00747 | BRD-A62743154 | BIMU-8 | HTR4 | serotonin receptor agonist | Details | |
| C00748 | BRD-A13293292 | BINA | GRM2 | glutamate receptor positive allosteric modulator | Details | |
| C00749 | BRD-K36467523 | bindarit | CCL2|CCL7|CCL8 | NFkB pathway inhibitor | Details | |
| C00750 | BRD-K03399463 | BIO-1211 | ITGA4|ITGB1 | integrin antagonist | Details | |
| C00751 | BRD-K21318844 | BIO-5192 | ITGA4|ITGB1 | integrin inhibitor | Details | |
| C00752 | BRD-K89210380 | biotin | ACACA|ACACB|HLCS|MCCC1|MCCC2|PC|PCCA|PCCB|SLC5A6 | vitamin B | Details | |
| C00753 | BRD-K47690382 | bipenamol | CTSC | dipeptidyl peptidase inhibitor | Details | |
| C00754 | BRD-A00546892 | biperiden | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|CHRNA2 | acetylcholine receptor antagonist | Details | |
| C00755 | BRD-K71221037 | birinapant | BIRC2|XIAP | XIAP inhibitor | Details | |
| C00756 | BRD-K64880136 | BIRT-377 | ICAM1 | lymphocyte function-associated antigen negative modulator | Details | |
| C00757 | BRD-K16180792 | bis(maltolato)oxovanadium(IV) | PTPN1 | tyrosine phosphatase inhibitor | Details | |
| C00758 | BRD-K39987650 | bisacodyl | laxative | Details | ||
| C00759 | BRD-K06543683 | bisindolylmaleimide-ix | AKT1|GSK3B|LCK|MAPK1|MAPK11|MAPK12|MAPK14|MAPK8|PRKCA|ROCK1|RPS6KB1|SIRT1 | PKC inhibitor | Details | |
| C00760 | BRD-M56276249 | bismuth(iii)-trifluoromethanesulfonate | direct substitution catalyst | Details | ||
| C00761 | BRD-M02179497 | bismuth-oxalate | Details | |||
| C00762 | BRD-A03880619 | bismuth-subcitrate-potassium | Details | |||
| C00763 | BRD-K65978409 | bismuth-subgallate | NOS1 | nitric oxide synthase inhibitor | Details | |
| C00764 | BRD-K80528473 | bismuth-subsalicylate | antacid | Details | ||
| C00765 | BRD-K00228584 | bisoctrizole | Details | |||
| C00766 | BRD-A89175223 | bisoprolol | ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C00767 | BRD-K41494493 | bisphenol-a | AR|ESR1|ESR2|ESRRG|PPARG | synthetic estrogen | Details | |
| C00768 | BRD-K39120595 | bithionol | ESR1|ESR2|MCL1 | autotaxin inhibitor | Details | |
| C00769 | BRD-K13756951 | bitopertin | SLC6A5|SLC6A9 | glycine transporter inhibitor; GlyT-1 inhibitor | Details | |
| C00770 | BRD-K77548206 | bitoscanate | anthelmintic agent | Details | ||
| C00771 | BRD-K28054654 | bivalirudin | F2 | thrombin inhibitor | Details | |
| C00772 | BRD-K26818574 | BIX-01294 | EHMT1|EHMT2 | histone lysine methyltransferase inhibitor | Details | |
| C00773 | BRD-K20290250 | BIX-02188 | MAP2K5 | MEK inhibitor | Details | |
| C00774 | BRD-K73368362 | BIX-02189 | MAP2K5|MAPK7 | MEK inhibitor | Details | |
| C00775 | BRD-K75282704 | BL-5583 | hypercalcaemic agent | Details | ||
| C00776 | BRD-A75817871 | blebbistatin-(+/-) | MYH2 | ATPase inhibitor | Details | |
| C00777 | BRD-K61295575 | blebbistatin-(-) | ATPase inhibitor | Details | ||
| C00778 | BRD-A94813917 | bleomycetin | EGFR expression inhibitor | Details | ||
| C00779 | BRD-A42083487 | bleomycin | LIG1|LIG3 | DNA synthesis inhibitor | Details | |
| C00780 | BRD-K25943794 | blonanserin | DRD2|HTR2A | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C00781 | BRD-K72898849 | BLU9931 | FGFR4 | FGFR inhibitor | Details | |
| C00782 | BRD-K94379058 | BML-190 | CNR2 | cannabinoid receptor inverse agonist | Details | |
| C00783 | BRD-K42624714 | BML-284 | WNT agonist | Details | ||
| C00784 | BRD-K15119094 | BMS-CCR2-22 | CCR2 | CC chemokine receptor antagonist | Details | |
| C00785 | BRD-K56509348 | BMS-182874 | EDNRA | endothelin receptor antagonist | Details | |
| C00786 | BRD-K95609758 | BMS-191011 | KCNMA1 | potassium channel activator | Details | |
| C00787 | BRD-K01231377 | BMS-191095 | KATP activator; potassium channel agonist | Details | ||
| C00788 | BRD-K62814476 | BMS-265246 | CDK1|CDK2 | CDK inhibitor | Details | |
| C00789 | BRD-K02950022 | BMS-299897 | gamma secretase inhibitor | Details | ||
| C00790 | BRD-K87956243 | BMS-309403 | FABP4 | fatty acid binding protein inhibitor | Details | |
| C00791 | BRD-K13566078 | BMS-345541 | CHUK|IKBKB | IKK inhibitor | Details | |
| C00792 | BRD-K43389698 | BMS-387032 | CDK2|CDK7|CDK9 | CDK inhibitor; cell cycle inhibitor; MCL1 inhibitor | Details | |
| C00793 | BRD-K22000702 | BMS-470539 | MC1R | melanocortin receptor agonist | Details | |
| C00794 | BRD-K34581968 | BMS-536924 | AKT1|CCNE1|CDK2|CYP3A4|ERBB2|IGF1R|KDR|LCK|MAPK1|MET|PDGFRA|PDGFRB | IGF-1 inhibitor | Details | |
| C00795 | BRD-K56932272 | BMS-566419 | IMPDH1|IMPDH2 | inosine monophosphate dehydrogenase inhibitor | Details | |
| C00796 | BRD-K20093108 | BMS-587101 | ITGAL|ITGB2 | integrin antagonist | Details | |
| C00797 | BRD-K07106112 | BMS-599626 | EGFR|ERBB2|ERBB4 | EGFR inhibitor; protein tyrosine kinase inhibitor | Details | |
| C00798 | BRD-K97883416 | BMS-626529 | HIV attachment inhibitor | Details | ||
| C00799 | BRD-K25991633 | BMS-649 | RXRA | retinoid receptor agonist | Details | |
| C00800 | BRD-K85649978 | BMS-688521 | ICAM1 | leukocyte function-associated antigen receptor antagonist; ICAM1 antagonist | Details |