CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C02701 | BRD-K90948141 | indiplon | GABRA1 | benzodiazepine receptor agonist | Details | |
| C02702 | BRD-K17894950 | indirubin | CDK1|CDK5|GSK3A | CDK inhibitor; glycogen synthase kinase inhibitor | Details | |
| C02703 | BRD-K19136521 | indirubin-3-monoxime | CDK1|CDK2|CDK5|CDK5R1|GSK3B | CDK inhibitor; glycogen synthase kinase inhibitor | Details | |
| C02704 | BRD-K17610631 | indisulam | CA1|CA12|CA14|CA2|CA6|CA7|CA9 | CDK inhibitor | Details | |
| C02705 | BRD-M08274809 | indium(iii)-isopropoxide | Details | |||
| C02706 | BRD-K42332878 | indium-tri(2-propanolate) | Details | |||
| C02707 | BRD-A16296925 | indobufen | PTGS1|PTGS2 | cyclooxygenase inhibitor; platelet aggregation inhibitor | Details | |
| C02708 | BRD-K80762071 | indocyanine-green | SLCO1B1 | contrast agent | Details | |
| C02709 | BRD-K01815685 | indole-3-carbinol | AHR | aryl hydrocarbon receptor agonist; indoleamine 2,3-dioxygenase inhibitor | Details | |
| C02710 | BRD-K09109825 | indole-3-pyrubate | melatonin receptor agonist | Details | ||
| C02711 | BRD-K57222227 | indomethacin | GLO1|PLA2G2A|PPARA|PPARG|PTGDR2|PTGR2|PTGS1|PTGS2|SLC46A1 | cyclooxygenase inhibitor | Details | |
| C02712 | BRD-A44090213 | indoprofen | CXCR1|CXCR2|PTGS1|PTGS2 | cyclooxygenase inhibitor; prostanoid receptor antagonist | Details | |
| C02713 | BRD-K76953762 | indoramin | ADRA1A|ADRA1B|ADRA1D|ADRA2B|ADRA2C | adrenergic receptor antagonist | Details | |
| C02714 | BRD-K93255255 | indoximod | IDO1 | indoleamine 2,3-dioxygenase inhibitor | Details | |
| C02715 | BRD-K93779381 | ingenol-mebutate | PRKCA|PRKCB|PRKCD|PRKCE|PRKCG | PKC activator | Details | |
| C02716 | BRD-K70177501 | INH1 | NDC80 | Hec1 inhibitor | Details | |
| C02717 | BRD-A71407503 | inimur | other antifungal | Details | ||
| C02718 | BRD-K11153516 | iniparib | PARP1 | PARP inhibitor | Details | |
| C02719 | BRD-K79612754 | inosine | PARP1|PNP | neurotrophic agent | Details | |
| C02720 | BRD-K52618540 | inositol | CDIPT|GBA | insulin sensitizer | Details | |
| C02721 | BRD-K82800842 | inositol-hexanicotinate | Details | |||
| C02722 | BRD-A29125379 | INS316 | purinergic receptor antagonist | Details | ||
| C02723 | BRD-K30968378 | INT-747 | FXR agonist | Details | ||
| C02724 | BRD-K33067152 | INT-767 | GPBAR1 | FXR agonist | Details | |
| C02725 | BRD-K88165431 | integrin-antagonist-1 | ITGAV|ITGB6 | integrin antagonist | Details | |
| C02726 | BRD-K43860855 | iobenguane | antineoplastic agent | Details | ||
| C02727 | BRD-A37492983 | iocetamic-acid | radiopaque medium | Details | ||
| C02728 | BRD-K67261995 | iodipamide | ALB | radiopaque medium | Details | |
| C02729 | BRD-A08660406 | iodixanol | radiopaque medium | Details | ||
| C02730 | BRD-K69216798 | iodoantipyrine | Details | |||
| C02731 | BRD-A46813902 | iododexetimide | acetylcholine receptor antagonist | Details | ||
| C02732 | BRD-K51918615 | iodophenpropit | HRH3|HRH4 | histamine receptor antagonist | Details | |
| C02733 | BRD-K75855670 | iodoquinol | antiseptic | Details | ||
| C02734 | BRD-A60217728 | iohexol | radiopaque medium | Details | ||
| C02735 | BRD-K75868704 | iopamidol | radiopaque medium | Details | ||
| C02736 | BRD-A42628519 | iopanic-acid | thyroid hormone inhibitor | Details | ||
| C02737 | BRD-K51956333 | iopodic-acid | Details | |||
| C02738 | BRD-A72075775 | iopromide | radiopaque medium | Details | ||
| C02739 | BRD-K98250023 | iothalamic-acid-d3 | radiopaque medium | Details | ||
| C02740 | BRD-A65818372 | ioversol | radiopaque medium | Details | ||
| C02741 | BRD-K84892605 | IOWH032 | CFTR | CFTR channel antagonist | Details | |
| C02742 | BRD-K79124250 | ioxaglic-acid | radiopaque medium | Details | ||
| C02743 | BRD-A09370961 | ioxilan | radiopaque medium | Details | ||
| C02744 | BRD-K70751730 | IOX1 | EGLN1|KDM3A|KDM4C|KDM6B | histone demethylase inhibitor | Details | |
| C02745 | BRD-K98251413 | IOX2 | EGLN1|KDM2A|KDM5C | hypoxia inducible factor inhibitor | Details | |
| C02746 | BRD-K38727704 | IPA-3 | PAK1 | p21 activated kinase inhibitor | Details | |
| C02747 | BRD-K82421491 | IPAG | Details | |||
| C02748 | BRD-K93468883 | IPI-145 | PIK3CA|PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C02749 | BRD-K66896231 | ipidacrine | ACHE | acetylcholinesterase inhibitor | Details | |
| C02750 | BRD-K51247865 | ipragliflozin-l-proline | SLC5A2 | sodium/glucose cotransporter inhibitor | Details | |
| C02751 | BRD-A47449001 | ipratropium | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor antagonist | Details | |
| C02752 | BRD-K93618743 | ipriflavone | bone resorption inhibitor | Details | ||
| C02753 | BRD-K88568253 | iproniazid | MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C02754 | BRD-K90574421 | ipsapirone | HTR1A | serotonin receptor agonist | Details | |
| C02755 | BRD-K60038276 | irbesartan | AGTR1|JUN|SLC10A1 | angiotensin receptor antagonist | Details | |
| C02756 | BRD-K08547377 | irinotecan | TOP1|TOP1MT | topoisomerase inhibitor | Details | |
| C02757 | BRD-K98357249 | IRL-2500 | EDNRB | endothelin receptor antagonist | Details | |
| C02758 | BRD-K87777313 | irosustat | CA2|STS | steroid sulfatase inhibitor | Details | |
| C02759 | BRD-K74195153 | irsogladine | PDE4A | phosphodiesterase inhibitor | Details | |
| C02760 | BRD-A26845397 | isamoltane | HTR1A|HTR1B | adrenergic receptor antagonist | Details | |
| C02761 | BRD-A17009129 | isavuconazole | CYP3A4 | cytochrome P450 inhibitor | Details | |
| C02762 | BRD-K95957366 | isaxonine | nerve growth factor agonist | Details | ||
| C02763 | BRD-K06762493 | isbufylline | phosphodiesterase inhibitor | Details | ||
| C02764 | BRD-K74759733 | isepamicin | protein synthesis inhibitor | Details | ||
| C02765 | BRD-A94055480 | ISO-1 | MIF | macrophage migration inhibiting factor inhibitor | Details | |
| C02766 | BRD-K96714749 | isobutamben | local anesthetic | Details | ||
| C02767 | BRD-K54057105 | isobutyramide | HBE1|HBG1 | gene expression stimulant | Details | |
| C02768 | BRD-K93332168 | isocarboxazid | MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C02769 | BRD-A93353767 | isoconazole | CYP17A1 | fungal lanosterol demethylase inhibitor | Details | |
| C02770 | BRD-K60241851 | isodibut | aldehyde reductase inhibitor | Details | ||
| C02771 | BRD-A24587114 | isoetharine | ADRB1|ADRB2 | adrenergic receptor agonist | Details | |
| C02772 | BRD-A07704283 | isofloxythepin | dopamine receptor antagonist | Details | ||
| C02773 | BRD-K29173907 | isoflupredone-acetate | NR3C1 | Details | ||
| C02774 | BRD-A31564021 | isoflurane | ATP2C1|ATP5D|CALM1|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GLRA1|GLRB|GRIA1|KCNA1|KCNK10|KCNK18|KCNK2|KCNK3|KCNK9 | inhaled anaesthetic | Details | |
| C02775 | BRD-K56575995 | isoflurophate | ACHE|BCHE | cholinesterase inhibitor | Details | |
| C02776 | BRD-K66480997 | isoguvacine | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRR1|GABRR2|GABRR3 | benzodiazepine receptor agonist | Details | |
| C02777 | BRD-A02232681 | isoleucine | ACADSB|BCAT1|BCAT2|IARS|IARS2 | Details | ||
| C02778 | BRD-K33583600 | isoliquiritigenin | GABBR1 | guanylate cyclase activator | Details | |
| C02779 | BRD-A64743628 | isometheptene-mucate | ADRA1A|SLC18A2 | Details | ||
| C02780 | BRD-K87202646 | isoniazid | CYP1A2|CYP2C19|CYP2C8|CYP2E1|CYP3A4 | FABI inhibitor | Details | |
| C02781 | BRD-K37851352 | isopentyl-4-methoxycinnamate | Details | |||
| C02782 | BRD-A04322457 | isoprenaline | ADRB1|ADRB2|ADRB3|MAPK1|PIK3R1|PIK3R2|PIK3R3 | adrenergic receptor agonist | Details | |
| C02783 | BRD-K14127446 | isopropamide-iodide | CHRM3|CHRM4 | acetylcholine receptor antagonist | Details | |
| C02784 | BRD-K13409143 | isopropyl-myristate | Details | |||
| C02785 | BRD-K30758549 | isopropyl-palmitate | cosmetic moisturizer | Details | ||
| C02786 | BRD-A75140635 | isoquinoline,-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, | Details | |||
| C02787 | BRD-K47178855 | isosorbide | nitric oxide stimulant | Details | ||
| C02788 | BRD-K55853390 | isosorbide-dinitrate | GUCY1A2|GUCY1A3|GUCY1B2|GUCY1B3|NPR1 | nitric oxide stimulant | Details | |
| C02789 | BRD-K82225283 | isosorbide-mononitrate | GUCY1A2|GUCY1A3|GUCY1B2|GUCY1B3 | nitric oxide stimulant | Details | |
| C02790 | BRD-A96529864 | isosteviol | Details | |||
| C02791 | BRD-A02933148 | isotiquimide | Details | |||
| C02792 | BRD-K76723084 | isotretinoin | RARA|RARB|RARG | retinoid receptor agonist | Details | |
| C02793 | BRD-K90069354 | isovaleramide | alcohol dehydrogenase inhibitor | Details | ||
| C02794 | BRD-K92116564 | isoxepac | anti-inflammatory agent | Details | ||
| C02795 | BRD-A75552914 | isoxicam | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C02796 | BRD-A16700644 | isoxsuprine | ADRB2 | adrenergic receptor agonist | Details | |
| C02797 | BRD-K64881305 | ispinesib | KIF11 | kinesin inhibitor | Details | |
| C02798 | BRD-A90799790 | isradipine | CACNA1C|CACNA1D|CACNA1F|CACNA1H|CACNA1S|CACNA2D1|CACNA2D2|CACNB2 | calcium channel blocker | Details | |
| C02799 | BRD-K12826175 | ISRIB | EIF2A|EIF2AK3 | eukaryotic translation initiation factor inhibitor; PERK inhibitor | Details | |
| C02800 | BRD-K95412502 | istaroxime | ATP1A1 | ATPase inhibitor | Details |