CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C05101 | BRD-K65989725 | sudan-iv | Details | |||
| C05102 | BRD-K21547160 | sufentanil | OPRD1|OPRK1|OPRM1 | opioid receptor modulator | Details | |
| C05103 | BRD-K44133266 | sulbactam | beta lactamase inhibitor | Details | ||
| C05104 | BRD-A63431791 | sulbactam-pivoxil | beta lactamase inhibitor | Details | ||
| C05105 | BRD-K72384124 | sulbentine | other antifungal | Details | ||
| C05106 | BRD-K12539416 | sulbutiamine | acetylcholine receptor antagonist | Details | ||
| C05107 | BRD-A70649075 | sulconazole | sterol demethylase inhibitor | Details | ||
| C05108 | BRD-K59983611 | sulfabenzamide | bacterial antifolate | Details | ||
| C05109 | BRD-K13486660 | sulfacarbamide | Details | |||
| C05110 | BRD-K21520694 | sulfacetamide | PABA antagonist | Details | ||
| C05111 | BRD-K32021043 | sulfachlorpyridazine | bacterial antifolate | Details | ||
| C05112 | BRD-K32273377 | sulfadiazine | bacterial antifolate | Details | ||
| C05113 | BRD-K55250441 | sulfadoxine | dihydropteroate synthase inhibitor | Details | ||
| C05114 | BRD-K50859149 | sulfafurazole | bacterial antifolate | Details | ||
| C05115 | BRD-K45086103 | sulfaguanidine | bacterial antifolate | Details | ||
| C05116 | BRD-K93524252 | sulfamerazine | bacterial antifolate | Details | ||
| C05117 | BRD-K87492696 | sulfameter | DHFR | dihydrofolate reductase inhibitor | Details | |
| C05118 | BRD-K11640013 | sulfamethazine | PABA antagonist | Details | ||
| C05119 | BRD-K31682896 | sulfamethizole | bacterial antifolate | Details | ||
| C05120 | BRD-K28494619 | sulfamethoxazole | PABA antagonist | Details | ||
| C05121 | BRD-K00938507 | sulfamethoxypyridazine | bacterial antifolate | Details | ||
| C05122 | BRD-K17205817 | sulfametopyrazine | PABA antagonist | Details | ||
| C05123 | BRD-K14116214 | sulfamonomethoxine | bacterial antifolate | Details | ||
| C05124 | BRD-K19742012 | sulfamoxole | PABA antagonist | Details | ||
| C05125 | BRD-K02594908 | sulfanilamide | CYP2C19|CYP2C9|CYP2D6|CYP2E1|CYP3A4 | carbonic anhydrase inhibitor | Details | |
| C05126 | BRD-K04254814 | sulfanilate-zinc | Details | |||
| C05127 | BRD-K76845197 | sulfanitran | Details | |||
| C05128 | BRD-K10671814 | sulfaphenazole | DHPS | dihydropteroate synthetase inhibitor | Details | |
| C05129 | BRD-K41406082 | sulfapyridine | PABA antagonist | Details | ||
| C05130 | BRD-K71133585 | sulfaquinoxaline | vitamin K antagonist | Details | ||
| C05131 | BRD-K10670311 | sulfasalazine | ACAT1|ALOX5|CHUK|IKBKB|PLA2G1B|PPARG|PTGS1|PTGS2|SLC46A1|SLC7A11|TBXAS1 | cyclooxygenase inhibitor | Details | |
| C05132 | BRD-K14705039 | sulfathiazole | dihydropteroate synthase inhibitor | Details | ||
| C05133 | BRD-A36217750 | sulfinpyrazone | ABCC1|ABCC2|FPR1|SLC22A12 | uricosuric blocker | Details | |
| C05134 | BRD-K84810336 | sulfisoxazole-acetyl | folic acid antagonist | Details | ||
| C05135 | BRD-A58955223 | sulforaphane | NFE2L2 | anticancer agent; aryl hydrocarbon receptor antagonist | Details | |
| C05136 | BRD-A13946108 | sulindac | AKR1B1|MAPK3|PPARD|PTGDR2|PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C05137 | BRD-K38602774 | sulisobenzone | Details | |||
| C05138 | BRD-A22081593 | sulmazole | adenosine receptor antagonist | Details | ||
| C05139 | BRD-K29570907 | sulmetozine | GAST | gastrin inhibitor | Details | |
| C05140 | BRD-A34205397 | suloctidil | adrenergic receptor antagonist | Details | ||
| C05141 | BRD-K71125014 | sulphadimethoxine | dihydropteroate synthetase inhibitor | Details | ||
| C05142 | BRD-A55272860 | sulpiride | dopamine receptor antagonist | Details | ||
| C05143 | BRD-K30485548 | sumanirole | DRD2 | dopamine receptor agonist | Details | |
| C05144 | BRD-K50938287 | sumatriptan | HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR5A|HTR6|HTR7 | serotonin receptor agonist | Details | |
| C05145 | BRD-K36274133 | SUN-B-8155 | CALCR | calcitonin agonist | Details | |
| C05146 | BRD-K71250460 | SUN-11602 | FGFR1 | fibroblast growth factor mimetic | Details | |
| C05147 | BRD-K42828737 | sunitinib | CSF1R|FGFR1|FLT1|FLT3|FLT4|KDR|KIT|PDGFRA|PDGFRB|RET | FLT3 inhibitor; KIT inhibitor; PDGFR tyrosine kinase receptor inhibitor; RET tyrosine kinase inhibitor; VEGFR inhibitor | Details | |
| C05148 | BRD-A98427211 | suplatast | histamine release inhibitor; immunoglobulin inhibitor | Details | ||
| C05149 | BRD-A34006693 | suprofen | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C05150 | BRD-K70327167 | suramin | F2|FSHR|P2RY1|P2RY11|P2RY13|P2RY2|PLA2G2A|RYR1|RYR2|SIRT5 | DNA synthesis inhibitor | Details | |
| C05151 | BRD-K98557884 | suritozole | GABBR1 | GABA receptor inverse agonist | Details | |
| C05152 | BRD-K86670086 | sutezolid | protein synthesis inhibitor | Details | ||
| C05153 | BRD-K94293891 | suvorexant | HCRTR1|HCRTR2 | orexin receptor antagonist | Details | |
| C05154 | BRD-K78815826 | suxibuzone | cyclooxygenase inhibitor | Details | ||
| C05155 | BRD-K75911534 | SU014813 | KDR | PDGFR tyrosine kinase receptor inhibitor; VEGFR inhibitor | Details | |
| C05156 | BRD-K32730239 | SU3327 | MAPK8 | JNK inhibitor | Details | |
| C05157 | BRD-K94883909 | SU9516 | CDK1|CDK2|CDK4|CDK5 | CDK inhibitor | Details | |
| C05158 | BRD-K15170068 | swainsonine | MAN2A1 | alpha mannosidase inhibitor | Details | |
| C05159 | BRD-K45385835 | SX-011 | MAPK14 | MAP kinase inhibitor | Details | |
| C05160 | BRD-K72106461 | SYM-2081 | GRIK1|GRIK2|GRIK3|GRIK4|GRIK5|SLC1A2 | kainate receptor antagonist | Details | |
| C05161 | BRD-A77218119 | SYM-2206 | GRIA1|GRIA2|GRIA3|GRIA4 | glutamate receptor antagonist | Details | |
| C05162 | BRD-K33642804 | symclosene | Details | |||
| C05163 | BRD-A04327189 | synephrine | ADRA1A | adrenergic receptor agonist | Details | |
| C05164 | BRD-K12745498 | S1P1-agonist-III | S1PR1 | sphingosine kinase inhibitor | Details | |
| C05165 | BRD-K02501528 | S18986 | GRIA1|GRIA2|GRIA3|GRIA4 | glutamate receptor modulator | Details | |
| C05166 | BRD-K48826825 | S26948 | PPARG | PPAR receptor agonist | Details | |
| C05167 | BRD-K96798615 | S4 | CA12|CA9 | carbonic anhydrase inhibitor | Details | |
| C05168 | BRD-K31843556 | T-0070907 | PPARG | PPAR receptor antagonist | Details | |
| C05169 | BRD-K63516691 | T-0156 | PDE5A | phosphodiesterase inhibitor | Details | |
| C05170 | BRD-K23383398 | T-0901317 | NCOA1|NCOA2|NR1H2|NR1H3|NR1I2|RXRB | LXR agonist | Details | |
| C05171 | BRD-K84925803 | T-5224 | JUN | AP inhibitor | Details | |
| C05172 | BRD-K83492904 | T-5601640 | LIMK2 | LIM kinase inhibitor | Details | |
| C05173 | BRD-K09001147 | T-62 | ADORA2A | adenosine receptor modulator | Details | |
| C05174 | BRD-K79856806 | TA-01 | CSNK1D|CSNK1E|MAPK14 | casein kinase inhibitor; MAP kinase inhibitor | Details | |
| C05175 | BRD-K53600683 | tabimorelin | GHSR | growth hormone secretagogue receptor agonist | Details | |
| C05176 | BRD-K73237276 | tacalcitol | VDR | vitamin D receptor agonist | Details | |
| C05177 | BRD-K52313696 | tacedinaline | HDAC1 | HDAC inhibitor | Details | |
| C05178 | BRD-K81473089 | tacrine | ACHE|BCHE | acetylcholinesterase inhibitor | Details | |
| C05179 | BRD-K69608737 | tacrolimus | FKBP1A | calcineurin inhibitor | Details | |
| C05180 | BRD-K93645900 | tadalafil | PDE11A|PDE5A | phosphodiesterase inhibitor | Details | |
| C05181 | BRD-K23728141 | tafamidis-meglumine | TTR | transthyretin amyloid inhibitor | Details | |
| C05182 | BRD-A78965079 | tafenoquine | antimalarial agent | Details | ||
| C05183 | BRD-A73556557 | tagatose | PYGL | phosphorylase inhibitor | Details | |
| C05184 | BRD-K57155378 | TAK-063 | PDE10A | phosphodiesterase inhibitor | Details | |
| C05185 | BRD-K38793468 | TAK-220 | CCR5 | CC chemokine receptor antagonist | Details | |
| C05186 | BRD-K80343549 | TAK-285 | ERBB2 | EGFR inhibitor | Details | |
| C05187 | BRD-K67262033 | TAK-593 | PDGFRA | VEGFR inhibitor | Details | |
| C05188 | BRD-K31866293 | TAK-632 | BRAF | RAF inhibitor | Details | |
| C05189 | BRD-K52751261 | TAK-715 | MAPK14 | p38 MAPK inhibitor | Details | |
| C05190 | BRD-K26667523 | TAK-733 | MAP2K1 | MEK inhibitor | Details | |
| C05191 | BRD-K58501140 | TAK-875 | FFAR1 | insulin secretagogue | Details | |
| C05192 | BRD-K01683783 | TAK-901 | AURKB | Aurora kinase inhibitor | Details | |
| C05193 | BRD-K48059512 | TAK-960 | PLK1 | PLK inhibitor | Details | |
| C05194 | BRD-K37419961 | talabostat | DPP4 | dipeptidyl peptidase inhibitor; fibroblast activation protein inhibitor | Details | |
| C05195 | BRD-K50498985 | taladegib | DHH|IHH|SMO | smoothened receptor antagonist | Details | |
| C05196 | BRD-K80359953 | talampanel | GRIA1|GRIA2|GRIA3|GRIA4 | glutamate receptor antagonist | Details | |
| C05197 | BRD-A95755460 | talarozole | CYP26A1 | cytochrome P450 inhibitor | Details | |
| C05198 | BRD-K95142244 | talazoparib | PARP2 | PARP inhibitor | Details | |
| C05199 | BRD-M92352362 | talc | Details | |||
| C05200 | BRD-A94276798 | talinolol | ADRB1 | adrenergic receptor antagonist | Details |