CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C03701 | BRD-A00100033 | nifurtimox | DNA inhibitor | Details | ||
| C03702 | BRD-K59333713 | niguldipine-(S)-(+) | ADRA1A | adrenergic receptor antagonist | Details | |
| C03703 | BRD-K91544578 | nikethamide | immunostimulant | Details | ||
| C03704 | BRD-K81528515 | nilotinib | ABL1|KIT | Abl kinase inhibitor; Bcr-Abl kinase inhibitor | Details | |
| C03705 | BRD-K23566484 | nilutamide | AR | androgen receptor antagonist | Details | |
| C03706 | BRD-A84687895 | nilvadipine | CACNA1C|CACNA1D|CACNA1S|CACNA2D1|CACNA2D3|CACNB2 | calcium channel blocker | Details | |
| C03707 | BRD-K76775527 | nimesulide | LTF|PLA2G2E|PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C03708 | BRD-A58048407 | nimodipine | AHR|CACNA1C|CACNA1D|CACNA1F|CACNA1S|CACNB1|CACNB2|CACNB3|CACNB4|CFTR|NR3C2 | calcium channel blocker | Details | |
| C03709 | BRD-K79145628 | nimorazole | bacterial DNA inhibitor | Details | ||
| C03710 | BRD-K13240081 | nimustine | DNA alkylating agent | Details | ||
| C03711 | BRD-K49075727 | nintedanib | FGFR1|FGFR2|FGFR3|FGFR4|FLT1|FLT4|KDR|PDGFRA|PDGFRB | FGFR inhibitor; PDGFR tyrosine kinase receptor inhibitor; VEGFR inhibitor | Details | |
| C03712 | BRD-K54955827 | niraparib | PARP1 | PARP inhibitor | Details | |
| C03713 | BRD-K53123955 | niridazole | phosphofructokinase inhibitor | Details | ||
| C03714 | BRD-A41063939 | nisin | bacterial cell wall synthesis inhibitor | Details | ||
| C03715 | BRD-A84465106 | nisoldipine | CACNA1C|CACNA1D|CACNA1F|CACNA1S|CACNA2D1|CACNB2 | calcium channel blocker | Details | |
| C03716 | BRD-A95696066 | nisoxetine | SLC6A2|SLC6A3|SLC6A4 | norepinephrine reuptake inhibitor | Details | |
| C03717 | BRD-K56707426 | nitarsone | Details | |||
| C03718 | BRD-K96471533 | nitazoxanide | pyruvate ferredoxin oxidoreductase inhibitor | Details | ||
| C03719 | BRD-K75551531 | nitecapone | COMT | catechol O methyltransferase inhibitor | Details | |
| C03720 | BRD-K47887731 | nitenpyram | Details | |||
| C03721 | BRD-K39467894 | nithiamide | bacterial DNA inhibitor | Details | ||
| C03722 | BRD-K01109406 | nitisinone | HPD | hydroxyphenylpyruvate dioxygenase inhibitor | Details | |
| C03723 | BRD-A02006392 | nitrendipine | CACNA1C|CACNA1D|CACNA1H|CACNA1S|CACNA2D1|CACNA2D2|CACNB2|CACNG1|KCNN4 | calcium channel blocker | Details | |
| C03724 | BRD-K28453807 | nitrocaramiphen | CHRM1 | cholinergic receptor antagonist | Details | |
| C03725 | BRD-K76927775 | nitrofurantoin | DNA inhibitor | Details | ||
| C03726 | BRD-K79092138 | nitrofurazone | bacterial DNA inhibitor | Details | ||
| C03727 | BRD-K76381435 | nitromide | Details | |||
| C03728 | BRD-K08927448 | nitrosodimethylurea | DNA synthesis inhibitor | Details | ||
| C03729 | BRD-K97534525 | nitroxoline | METAP2 | cathepsin inhibitor | Details | |
| C03730 | BRD-K73589491 | nizatidine | HRH2 | histamine receptor antagonist | Details | |
| C03731 | BRD-K84011460 | nizofenone | ion channel antagonist | Details | ||
| C03732 | BRD-K47441935 | NK-252 | NFE2L2 | NRF2 activator | Details | |
| C03733 | BRD-K74796838 | NKP-1339 | HSP inhibitor | Details | ||
| C03734 | BRD-A75015151 | NKY-80 | ADCY5 | adenylyl cyclase inhibitor | Details | |
| C03735 | BRD-A62133859 | NLG919 | IDO1 | indoleamine 2,3-dioxygenase inhibitor | Details | |
| C03736 | BRD-K62414032 | NMDA | GRIN1|GRIN2A|GRIN2B|GRIN2C|GRIN2D | glutamate receptor agonist | Details | |
| C03737 | BRD-K58770988 | NMS-E973 | HSP inhibitor | Details | ||
| C03738 | BRD-K54170555 | NMS-P715 | protein kinase inhibitor | Details | ||
| C03739 | BRD-K83699324 | NMS-1286937 | FLT3|PLK1|PLK2|PLK3 | PLK inhibitor | Details | |
| C03740 | BRD-K26253904 | NMS-873 | VCP | ATPase inhibitor | Details | |
| C03741 | BRD-A66966115 | NM107 | RNA polymerase inhibitor | Details | ||
| C03742 | BRD-K85015012 | NNC-05-2090 | SLC6A12 | GABA uptake inhibitor; GAT inhibitor | Details | |
| C03743 | BRD-K78122587 | NNC-55-0396 | CATSPER1|CATSPER2|CATSPER3|CATSPER4 | T-type calcium channel blocker | Details | |
| C03744 | BRD-K72904818 | NNC-63-0532 | OPRL1 | opioid receptor agonist | Details | |
| C03745 | BRD-K42221274 | NNC-711 | SIGMAR1|SLC6A1 | GABA uptake inhibitor | Details | |
| C03746 | BRD-K08807999 | NO-ASA | PTGS2 | cyclooxygenase inhibitor | Details | |
| C03747 | BRD-K06753942 | nobiletin | MAP2K1 | MEK inhibitor | Details | |
| C03748 | BRD-K12539581 | nocodazole | HPGDS | tubulin polymerization inhibitor | Details | |
| C03749 | BRD-K36636143 | nolatrexed | TYMS | thymidylate synthase inhibitor | Details | |
| C03750 | BRD-K27351809 | nomegestrol-acetate | PGR | progesterone receptor agonist | Details | |
| C03751 | BRD-A29644307 | nomifensine | DRD2|MAOA|MAOB|MPO|SLC6A2|SLC6A3 | dopamine uptake inhibitor; noradrenaline uptake inhibitor | Details | |
| C03752 | BRD-K05907307 | nonivamide | TRPV1 | TRPV agonist | Details | |
| C03753 | BRD-K88625236 | nonoxynol-9 | membrane integrity inhibitor | Details | ||
| C03754 | BRD-K36381762 | nor-Binaltorphimine-dihydrochloride | OPRD1|OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C03755 | BRD-K63165456 | norcyclobenzaprine | adrenergic receptor agonist; serotonin receptor antagonist | Details | ||
| C03756 | BRD-K42504537 | norelgestromin | PGR | Details | ||
| C03757 | BRD-K87349682 | norepinephrine | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|ADRB1|ADRB2|ADRB3|PAH|SLC18A1|SLC18A2 | adrenergic receptor agonist | Details | |
| C03758 | BRD-K92073408 | norethindrone | PGR | progesterone receptor agonist | Details | |
| C03759 | BRD-A09349126 | norethindrone-acetate | progesterone receptor agonist | Details | ||
| C03760 | BRD-K07625016 | norethisterone-enanthate | contraceptive agent | Details | ||
| C03761 | BRD-A00758722 | noretynodrel | PGR | progestogen hormone | Details | |
| C03762 | BRD-K11196887 | norfloxacin | TOP2A | bacterial DNA gyrase inhibitor | Details | |
| C03763 | BRD-A79769222 | norfluoxetine | HTR2B | selective serotonin reuptake inhibitor (SSRI) | Details | |
| C03764 | BRD-K38041788 | norgestimate | ESR1|PGR | progesterone receptor agonist | Details | |
| C03765 | BRD-A14886633 | norgestrel | PGR | progesterone receptor agonist | Details | |
| C03766 | BRD-A24543851 | nornicotine | acetylcholine receptor agonist | Details | ||
| C03767 | BRD-K91263825 | nortriptyline | ADRA1A|ADRA1B|ADRA1D|ADRA2A|ADRA2B|ADRA2C|ADRB1|ADRB2|ADRB3|CHRM1|CHRM2|CHRM3|CHRM4|CHRM5|DRD2|HRH1|HTR1A|HTR2A|HTR2C|HTR6|KCNJ10|PGRMC1|SIGMAR1|SLC6A2|SLC6A4 | tricyclic antidepressant | Details | |
| C03768 | BRD-A08791201 | norvancomycin | Details | |||
| C03769 | BRD-K89237706 | noscapine | SIGMAR1 | bradykinin receptor antagonist; tubulin polymerization inhibitor | Details | |
| C03770 | BRD-K11411329 | NOV-002 | GSR|GSTM2 | Details | ||
| C03771 | BRD-K85307935 | novobiocin | bacterial DNA gyrase inhibitor | Details | ||
| C03772 | BRD-K58277159 | NPC-01 | steroid | Details | ||
| C03773 | BRD-K65275554 | NPC-15199 | PPARG | ICAM1 antagonist | Details | |
| C03774 | BRD-K89272762 | NPPB | ANO1|CLCN2|CLCN7|TRPA1 | chloride channel blocker | Details | |
| C03775 | BRD-K75506300 | NPS-2143 | CASR | calcium receptor antagonist | Details | |
| C03776 | BRD-K95600043 | NPY-5RA972 | NPY5R | neuropeptide receptor antagonist | Details | |
| C03777 | BRD-K61918008 | NQDI-1 | CASP3 | caspase inhibitor | Details | |
| C03778 | BRD-K21865955 | NS-018 | JAK1|JAK2|JAK3|TYK2 | JAK inhibitor | Details | |
| C03779 | BRD-K94342292 | NS-11021 | KCNMA1 | calcium-activated potassium channel activator | Details | |
| C03780 | BRD-K73738482 | NS-1643 | KCNH2|KCNH6|KCNMA1 | voltage-gated potassium channel activator | Details | |
| C03781 | BRD-K03808106 | NS-19504 | KCNMA1 | calcium-activated potassium channel activator | Details | |
| C03782 | BRD-K37602296 | NS-309 | KCNN1|KCNN2|KCNN3|KCNN4 | calcium-activated potassium channel activator | Details | |
| C03783 | BRD-K24434292 | NS-3623 | KCNH2 | voltage-gated potassium channel activator | Details | |
| C03784 | BRD-A23155040 | NS-3861 | CHRNA3|CHRNB4 | acetylcholine receptor agonist | Details | |
| C03785 | BRD-K93314017 | NS-5806 | KCND3 | voltage-gated potassium channel activator | Details | |
| C03786 | BRD-K22667752 | NS-8 | KCNMA1 | potassium channel agonist | Details | |
| C03787 | BRD-K34624869 | NS-8593 | KCNN1|KCNN2|KCNN3 | calcium-activated potassium channel modulator | Details | |
| C03788 | BRD-K40176866 | NS-9283 | CHRNA4 | acetylcholine receptor allosteric modulator | Details | |
| C03789 | BRD-A80213327 | NSC-23766 | Ras GTPase inhibitor | Details | ||
| C03790 | BRD-K99170882 | NSC-319726 | p53 activator | Details | ||
| C03791 | BRD-K13169950 | NSC-3852 | HDAC1 | HDAC inhibitor | Details | |
| C03792 | BRD-A67975844 | NSC-405020 | MMP1 | matrix metalloprotease inhibitor | Details | |
| C03793 | BRD-K64874225 | NSC-4644 | PYGM | ACAT inhibitor; sterol regulatory element binding protein (SREBP) inhibitor | Details | |
| C03794 | BRD-K62949423 | NSC-625987 | CDK2|CDK4 | CDK inhibitor | Details | |
| C03795 | BRD-K81197548 | NSC-632839 | SENP2|USP1|USP2|USP7 | ubiquitin specific protease inhibitor | Details | |
| C03796 | BRD-K03109492 | NSC-663284 | CDC25A|CDC25B|CDC25C | CDC inhibitor | Details | |
| C03797 | BRD-K20605374 | NSC-697923 | UBE2N | ubiquitin-conjugating enzyme inhibitor | Details | |
| C03798 | BRD-K68143200 | NSC-95397 | CDC25A|CDC25B | CDC inhibitor | Details | |
| C03799 | BRD-K49811169 | NSC-9965 | CHRNA4|CHRNB2 | acetylcholine receptor antagonist | Details | |
| C03800 | BRD-K73799155 | NSC5844 | CCR1 | CC chemokine receptor agonist | Details |