CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C05201 | BRD-K75615183 | talipexole | ADRA2A|DRD2|HTR3A | adrenergic receptor agonist; dopamine receptor agonist | Details | |
| C05202 | BRD-K17555800 | talmapimod | MAPK11|MAPK14 | p38 MAPK inhibitor | Details | |
| C05203 | BRD-K47095176 | talnetant | TACR2|TACR3 | tachykinin antagonist | Details | |
| C05204 | BRD-A98378129 | talniflumate | CLCA1 | cyclooxygenase inhibitor | Details | |
| C05205 | BRD-A02532772 | talopram | SLC6A2 | adrenergic inhibitor | Details | |
| C05206 | BRD-K93869735 | taltirelin | TRHR | thyrotropin releasing hormone receptor agonist | Details | |
| C05207 | BRD-K87512222 | taltobulin | tubulin polymerization inhibitor | Details | ||
| C05208 | BRD-K72231366 | TAME | Details | |||
| C05209 | BRD-K36627727 | tamibarotene | RARA|RARB | retinoid receptor agonist | Details | |
| C05210 | BRD-K93754473 | tamoxifen | EBP|ESR1|ESR2|GPER1|PRKCA|PRKCB|PRKCD|PRKCE|PRKCG|PRKCI|PRKCQ|PRKCZ | estrogen receptor antagonist; selective estrogen receptor modulator (SERM) | Details | |
| C05211 | BRD-K74339692 | tamsulosin | ADRA1A|ADRA1B|ADRA1D | adrenergic receptor antagonist | Details | |
| C05212 | BRD-K99604664 | tanaproget | PGR | progesterone receptor agonist | Details | |
| C05213 | BRD-K65904673 | tandospirone | HTR1A | serotonin receptor agonist | Details | |
| C05214 | BRD-K89162000 | tandutinib | CSF1R|FLT3|KIT|PDGFD|PDGFRB | FLT3 inhibitor; KIT inhibitor; PDGFR tyrosine kinase receptor inhibitor | Details | |
| C05215 | BRD-K81473043 | tanespimycin | HSP90AA1 | HSP inhibitor | Details | |
| C05216 | BRD-K25186396 | tangeritin | cell cycle inhibitor | Details | ||
| C05217 | BRD-K67392463 | tannic-acid | ANO1 | PARG inhibitor | Details | |
| C05218 | BRD-K34073885 | tanshinone-i | IFNG | AP inhibitor | Details | |
| C05219 | BRD-K00141480 | tanshinone-iia | IL1B|NR1I2|TNF | anti-inflammatory agent; interleukin inhibitor | Details | |
| C05220 | BRD-K25699529 | tapentadol | HTR3A|OPRD1|OPRK1|OPRM1|SLC6A2|SLC6A4 | opioid receptor agonist | Details | |
| C05221 | BRD-K88854110 | taprenepag | PTGER2 | prostaglandin receptor agonist | Details | |
| C05222 | BRD-K59390331 | tarafenacin | CHRM3 | acetylcholine receptor antagonist | Details | |
| C05223 | BRD-K35169477 | taranabant | CNR1 | cannabinoid receptor inverse agonist | Details | |
| C05224 | BRD-K59506194 | targinine | NOS3 | nitric oxide synthase inhibitor | Details | |
| C05225 | BRD-K09353376 | tariquidar | ABCB1 | P glycoprotein inhibitor | Details | |
| C05226 | BRD-K36474365 | tartaric-acid | ATP6V1C1|B3GAT1|DDX6|HIF1AN|TREM1 | antioxidant | Details | |
| C05227 | BRD-K09426783 | TAS-103 | TOP1 | topoisomerase inhibitor | Details | |
| C05228 | BRD-K44844162 | taselisib | PIK3CA | PI3K inhibitor | Details | |
| C05229 | BRD-K62971431 | tasimelteon | MTNR1A|MTNR1B | melatonin receptor agonist | Details | |
| C05230 | BRD-K42495768 | tasisulam | apoptosis stimulant | Details | ||
| C05231 | BRD-K14653796 | tasquinimod | HDAC4 | angiogenesis inhibitor; S100A9 inhibitor | Details | |
| C05232 | BRD-K10415035 | tasuldine | mucolytic agent | Details | ||
| C05233 | BRD-K51474575 | taurine | antioxidant | Details | ||
| C05234 | BRD-K81062487 | taurocholate | CEL|FABP6|SLCO1C1 | G protein-coupled receptor agonist | Details | |
| C05235 | BRD-K98765504 | taurolidine | apoptosis stimulant | Details | ||
| C05236 | BRD-K76713213 | tavaborole | leucyl-tRNA synthetase inhibitor | Details | ||
| C05237 | BRD-K94649603 | taxifolin | ADIPOR2 | opioid receptor antagonist | Details | |
| C05238 | BRD-K76841105 | tazarotene | RARA|RARB|RARG|RXRB | retinoid receptor agonist | Details | |
| C05239 | BRD-K11215326 | tazemetostat | EZH2 | histone lysine methyltransferase inhibitor | Details | |
| C05240 | BRD-A18611368 | tazobactam | beta lactamase inhibitor | Details | ||
| C05241 | BRD-K56405978 | TBA-354 | Details | |||
| C05242 | BRD-M77041484 | TBOA-(DL) | SLC1A1|SLC1A2|SLC1A3|SLC1A6|SLC1A7 | excitatory amino acid transporter inhibitor | Details | |
| C05243 | BRD-A12147465 | TC-A-2317 | AURKA | Aurora kinase inhibitor | Details | |
| C05244 | BRD-K29660062 | TC-ASK-10 | MAP3K5|MAP3K6 | MAP kinase inhibitor | Details | |
| C05245 | BRD-K15256258 | TC-E-5002 | KDM2A|KDM4A|KDM4C|KDM5A|KDM6A|KDM7A|PHF8 | histone demethylase inhibitor | Details | |
| C05246 | BRD-A66521565 | TC-E-5006 | APP | gamma secretase modulator | Details | |
| C05247 | BRD-K26041695 | TC-F-2 | FAAH | FAAH inhibitor | Details | |
| C05248 | BRD-K16497916 | TC-FPR-43 | FPR2 | formyl peptide receptor agonist | Details | |
| C05249 | BRD-K27010807 | TC-G-1000 | ADRA2A|ADRA2B|ADRA2C | adrenergic receptor agonist | Details | |
| C05250 | BRD-K76989898 | TC-G-1004 | ADORA2A | adenosine receptor antagonist | Details | |
| C05251 | BRD-K16939217 | TC-G-1005 | GPBAR1 | G protein-coupled receptor agonist | Details | |
| C05252 | BRD-K87199310 | TC-G-1008 | GPR39 | G protein-coupled receptor agonist | Details | |
| C05253 | BRD-K45044657 | TC-H-106 | HDAC1|HDAC2|HDAC3|HDAC8 | HDAC inhibitor | Details | |
| C05254 | BRD-K17621556 | TC-I-15 | ITGA2|ITGB1 | integrin inhibitor | Details | |
| C05255 | BRD-A83792282 | TC-I-2000 | TRPM8 | transient receptor potential channel antagonist | Details | |
| C05256 | BRD-K05262258 | TC-I-2014 | TRPM8 | transient receptor potential channel antagonist | Details | |
| C05257 | BRD-K32031961 | TC-LPA5-4 | LPAR5 | lysophosphatidic acid receptor antagonist | Details | |
| C05258 | BRD-K76792630 | TC-Mps1-12 | TTK | monopolar spindle 1 kinase inhibitor | Details | |
| C05259 | BRD-K78161388 | TC-N-1752 | SCN9A | sodium channel blocker | Details | |
| C05260 | BRD-K79608170 | TC-NTR1-17 | NTSR1 | neurotensin agonist | Details | |
| C05261 | BRD-K54297077 | TC-O-9311 | GPR139 | G protein-coupled receptor agonist | Details | |
| C05262 | BRD-K55013981 | TC-OT-39 | AVPR1A|OXT | oxytocin receptor agonist; vasopressin receptor agonist | Details | |
| C05263 | BRD-K34362291 | TC-S-7003 | LCK | src inhibitor | Details | |
| C05264 | BRD-K89517477 | TC-S-7004 | DYRK1A|DYRK1B | DYRK inhibitor | Details | |
| C05265 | BRD-K89584803 | TC-S-7005 | PLK2 | PLK inhibitor | Details | |
| C05266 | BRD-K51776215 | TC-S-7006 | MAP3K8 | MAP kinase inhibitor | Details | |
| C05267 | BRD-K21894922 | TC-S-7009 | EPAS1 | hypoxia inducible factor inhibitor | Details | |
| C05268 | BRD-K87461578 | TC-SP-14 | S1PR1 | sphingosine 1 phosphate receptor agonist | Details | |
| C05269 | BRD-K27536248 | TCID | Details | |||
| C05270 | BRD-K77915400 | TCN-238 | GRM4 | glutamate receptor positive allosteric modulator | Details | |
| C05271 | BRD-K09787262 | TCN201 | GRIN2A | glutamate receptor antagonist | Details | |
| C05272 | BRD-K68358632 | TCS-HDAC6-20b | HDAC6 | HDAC inhibitor | Details | |
| C05273 | BRD-K29424831 | TCS-OX2-29 | HCRTR2 | orexin receptor antagonist | Details | |
| C05274 | BRD-K08902330 | TCS-PIM-1-1 | PIM1 | Pim kinase inhibitor | Details | |
| C05275 | BRD-K49461364 | TCS-21311 | JAK3 | JAK inhibitor | Details | |
| C05276 | BRD-K19958299 | TCS-2210 | neural stem cell inducer | Details | ||
| C05277 | BRD-K55216666 | TCS-2314 | ITGA4|ITGB1 | integrin inhibitor | Details | |
| C05278 | BRD-K81935556 | TCS-3035 | GPR35 | G protein-coupled receptor agonist | Details | |
| C05279 | BRD-K81376179 | TCS-359 | FLT3 | FLT3 inhibitor | Details | |
| C05280 | BRD-A16560607 | TCS-5861528 | TRPA1 | transient receptor potential channel antagonist | Details | |
| C05281 | BRD-A50028488 | TCS2002 | GSK3B | glycogen synthase kinase inhibitor | Details | |
| C05282 | BRD-A13964793 | TC1 | BACE1 | beta-secretase inhibitor | Details | |
| C05283 | BRD-K24227647 | TC2559 | CHRNA4 | acetylcholine receptor agonist | Details | |
| C05284 | BRD-K06900071 | tebipenem | CNR1 | bacterial cell wall synthesis inhibitor | Details | |
| C05285 | BRD-K41662846 | tecalcet | CASR | calcium-sensing receptor agonist | Details | |
| C05286 | BRD-K48195801 | tecastemizole | KCNH2 | histamine receptor antagonist | Details | |
| C05287 | BRD-K24312986 | tecovirimat | orthopoxvirus egress inhibitor | Details | ||
| C05288 | BRD-K59436580 | tedizolid | bacterial 50S ribosomal subunit inhibitor | Details | ||
| C05289 | BRD-K89121095 | tedizolid-phosphate | protein synthesis inhibitor | Details | ||
| C05290 | BRD-K88743730 | tegaserod | HTR2A|HTR2B|HTR2C|HTR4 | serotonin receptor partial agonist | Details | |
| C05291 | BRD-K26701552 | tegobuvir | HCV inhibitor; protease inhibitor | Details | ||
| C05292 | BRD-K07712545 | teicoplanin | bacterial cell wall synthesis inhibitor | Details | ||
| C05293 | BRD-A09761158 | teicoplanin-A2-1 | bacterial cell wall synthesis inhibitor | Details | ||
| C05294 | BRD-K96571715 | teicoplanin-a2-3 | bacterial cell wall synthesis inhibitor | Details | ||
| C05295 | BRD-K51528698 | Teijin-compound-1 | CCR2 | CC chemokine receptor antagonist | Details | |
| C05296 | BRD-K72912098 | telaprevir | CTSA|PGR | HCV inhibitor | Details | |
| C05297 | BRD-K84564571 | telatinib | KDR | KIT inhibitor; PDGFR tyrosine kinase receptor inhibitor; VEGFR inhibitor | Details | |
| C05298 | BRD-K15976406 | telbivudine | TK2 | DNA polymerase inhibitor | Details | |
| C05299 | BRD-K91159026 | telcagepant | CALCRL|RAMP1 | calcitonin antagonist | Details | |
| C05300 | BRD-K06147391 | telenzepine | CHRM1 | acetylcholine receptor antagonist | Details |