CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C03501 | BRD-K63151507 | MNITMT | lymphocyte inhibitor | Details | ||
| C03502 | BRD-K42205652 | MNS-(3,4-Methylenedioxy-nitrostyrene) | SRC|SYK | src inhibitor; syk inhibitor | Details | |
| C03503 | BRD-K16485616 | mocetinostat | HDAC1|HDAC11|HDAC2|HDAC3 | HDAC inhibitor | Details | |
| C03504 | BRD-K07237224 | moclobemide | MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C03505 | BRD-A16332958 | modafinil | ADRA1B|SLC6A3 | adrenergic receptor agonist | Details | |
| C03506 | BRD-K25317177 | modaline | Details | |||
| C03507 | BRD-K34441861 | moexipril | ACE|ACE2 | angiotensin converting enzyme inhibitor | Details | |
| C03508 | BRD-K52598503 | mofegiline | MAOA|MAOB | monoamine oxidase inhibitor | Details | |
| C03509 | BRD-K49372556 | mofezolac | PTGS1 | cyclooxygenase inhibitor | Details | |
| C03510 | BRD-A87673115 | moguisteine | ATP-sensitive potassium channel inhibitor | Details | ||
| C03511 | BRD-K01291782 | molidustat | EGLN2 | hypoxia inducible factor inhibitor | Details | |
| C03512 | BRD-A65280694 | molindone | CHRM1|DRD2|HRH1|HTR1A|HTR2A | dopamine receptor antagonist | Details | |
| C03513 | BRD-K63861289 | molsidomine | GUCY1A3 | guanylate cyclase stimulant | Details | |
| C03514 | BRD-K50265942 | mometasone | NR3C1 | glucocorticoid receptor agonist | Details | |
| C03515 | BRD-K60640630 | mometasone-furoate | NR3C1 | glucocorticoid receptor agonist | Details | |
| C03516 | BRD-A78377521 | monastrol | KIF11 | kinesin inhibitor | Details | |
| C03517 | BRD-A06627858 | monensin | bacterial permeability inducer | Details | ||
| C03518 | BRD-K54262262 | monobenzone | TYR | melanin inhibitor | Details | |
| C03519 | BRD-A48938994 | monoctanoin | Details | |||
| C03520 | BRD-K52559566 | monosodium-alpha-luminol | Details | |||
| C03521 | BRD-A31454688 | monostearin | Details | |||
| C03522 | BRD-K69470111 | montelukast | ALOX5|CYSLTR1 | leukotriene receptor antagonist | Details | |
| C03523 | BRD-A51747092 | moprolol | adrenergic receptor antagonist | Details | ||
| C03524 | BRD-K21548250 | moracizine | SCN5A | sodium channel blocker | Details | |
| C03525 | BRD-K71454870 | morantel | acetylcholine receptor agonist | Details | ||
| C03526 | BRD-K11590034 | morin | ADORA2A|ESR2|FASN|MCL1|SLC22A12 | cytochrome P450 inhibitor | Details | |
| C03527 | BRD-A40546373 | morinidazole | CYP51A1 | other antibiotic | Details | |
| C03528 | BRD-K38938675 | morniflumate | anti-inflammatory agent | Details | ||
| C03529 | BRD-K57291914 | moroxydine | antiviral | Details | ||
| C03530 | BRD-A39052811 | mosapride | HTR4 | serotonin receptor agonist | Details | |
| C03531 | BRD-K99616396 | motesanib | FLT1|FLT4|KDR|KIT | KIT inhibitor; PDGFR tyrosine kinase receptor inhibitor; VEGFR inhibitor | Details | |
| C03532 | BRD-K11785681 | motolimod | TLR8 | toll-like receptor agonist | Details | |
| C03533 | BRD-K40831222 | moxalactam | bacterial cell wall synthesis inhibitor | Details | ||
| C03534 | BRD-K12742203 | moxaverine | phosphodiesterase inhibitor | Details | ||
| C03535 | BRD-K61988078 | moxidectin | chloride channel antagonist | Details | ||
| C03536 | BRD-K66615216 | moxifloxacin | TOP2A | bacterial DNA gyrase inhibitor | Details | |
| C03537 | BRD-K81144366 | moxisylyte | adrenergic receptor antagonist | Details | ||
| C03538 | BRD-K77771411 | moxonidine | ADRA2A|ADRA2B|ADRA2C | imidazoline receptor agonist | Details | |
| C03539 | BRD-A31095847 | mozavaptan | AVPR1A|AVPR1B|AVPR2 | vasopressin receptor antagonist | Details | |
| C03540 | BRD-K60690191 | MPEP | GRM1|GRM4|GRM5 | glutamate receptor antagonist | Details | |
| C03541 | BRD-K45551181 | MPI-0479605 | TTK | mitotic kinase inhibitor | Details | |
| C03542 | BRD-K18530250 | Mps-BAY-2a | TTK | monopolar spindle 1 kinase inhibitor | Details | |
| C03543 | BRD-K94853001 | Mps1-IN-1 | TTK | monopolar spindle 1 kinase inhibitor | Details | |
| C03544 | BRD-K43812936 | Mps1-IN-5 | protein kinase inhibitor | Details | ||
| C03545 | BRD-A30590053 | MR-16728 | acetylcholine release enhancer | Details | ||
| C03546 | BRD-K84883208 | MR-948 | TBXAS1 | thromboxane synthase inhibitor | Details | |
| C03547 | BRD-K44022883 | MRK-016 | GABRA1|GABRA2|GABRA3|GABRA5 | GABA receptor inverse agonist | Details | |
| C03548 | BRD-K57416838 | MRK-409 | benzodiazepine receptor agonist | Details | ||
| C03549 | BRD-K68795758 | MRK-560 | APP | gamma secretase inhibitor | Details | |
| C03550 | BRD-K37618799 | MRS-1220 | ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C03551 | BRD-M86143595 | MRS-3777 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C03552 | BRD-A06784547 | MRS1334 | ADORA3 | adenosine receptor antagonist | Details | |
| C03553 | BRD-A78093359 | MRS1845 | calcium channel blocker | Details | ||
| C03554 | BRD-K91135178 | MRS2578 | P2RY6 | purinergic receptor antagonist | Details | |
| C03555 | BRD-K10575656 | MRS3777 | ADORA2A | adenosine receptor antagonist | Details | |
| C03556 | BRD-K25143390 | MSX-122 | CXCR4 | CC chemokine receptor antagonist | Details | |
| C03557 | BRD-A28329383 | MTPG | GRM2|GRM3 | glutamate receptor antagonist | Details | |
| C03558 | BRD-K19061412 | mubritinib | EGFR|ERBB2 | protein tyrosine kinase inhibitor | Details | |
| C03559 | BRD-K15262564 | mupirocin | isoleucyl-tRNA synthetase inhibitor | Details | ||
| C03560 | BRD-K60441002 | muscimol | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRR1|GABRR2|GABRR3 | benzodiazepine receptor agonist | Details | |
| C03561 | BRD-K72078047 | MUT056399 | FABI inhibitor | Details | ||
| C03562 | BRD-K90524085 | MY-5445 | PDE5A | phosphodiesterase inhibitor; platelet aggregation inhibitor | Details | |
| C03563 | BRD-K92428153 | mycophenolate-mofetil | IMPDH1|IMPDH2 | dehydrogenase inhibitor; inositol monophosphatase inhibitor | Details | |
| C03564 | BRD-K63750851 | mycophenolic-acid | IMPDH1|IMPDH2 | dehydrogenase inhibitor; inositol monophosphatase inhibitor | Details | |
| C03565 | BRD-K43149758 | myricetin | PIK3CG | androgen receptor agonist; cytochrome P450 inhibitor | Details | |
| C03566 | BRD-K29834313 | myricitrin | NOS1|PRKCA | PKC inhibitor | Details | |
| C03567 | BRD-K88153212 | myristyl-nicotinate | topical sunscreen agent | Details | ||
| C03568 | BRD-K90410034 | M8-B | TRPM8 | transient receptor potential channel antagonist | Details | |
| C03569 | BRD-K57027742 | N-(2-chlorophenyl)-2-({(2E)-2-[1-(2-pyridinyl)ethylidene]hydrazino}carbothioyl)hydrazinecarbothioamide | Details | |||
| C03570 | BRD-K78844995 | N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide | sigma receptor ligand | Details | ||
| C03571 | BRD-K80653534 | N-acetyl-D-glucosamine | B4GALT1|B4GALT2|B4GALT3|B4GALT4|NAGK|NAGLU|NAGPA|RENBP | Details | ||
| C03572 | BRD-A24857382 | N-acetyl-tyrosine | Details | |||
| C03573 | BRD-K52523550 | N-acetylcarnosine | Details | |||
| C03574 | BRD-K28121004 | N-acetylglycyl-D-glutamic-acid | glutamate receptor agonist | Details | ||
| C03575 | BRD-A92872453 | N-acetylmannosamine | CHIT1 | Details | ||
| C03576 | BRD-K73700643 | N-acetyltryptamine | melatonin receptor agonist | Details | ||
| C03577 | BRD-K64422603 | N-alpha-Methylhistamine-dihydrochloride | HRH4 | histamine receptor agonist | Details | |
| C03578 | BRD-A33514596 | N-benzylnaltrindole | opioid receptor antagonist | Details | ||
| C03579 | BRD-K90042229 | N-cyanopyrrolidine | CTSK | Details | ||
| C03580 | BRD-K84517077 | N-demethylantipyrine | Details | |||
| C03581 | BRD-K28030264 | N-hydroxynicotinamide | Details | |||
| C03582 | BRD-K82236108 | N-methyl-(-)ephedrine-[1r,2s] | Details | |||
| C03583 | BRD-K33445938 | N-methylformamide | Details | |||
| C03584 | BRD-K60060639 | N-methyllidocaine-iodide | antiarrhythmic medication | Details | ||
| C03585 | BRD-K52732207 | N-methylpyrrolidone | Details | |||
| C03586 | BRD-K62056274 | N-methylquipazine | HTR1A|HTR1D|HTR2A|HTR2B|HTR2C|HTR3A|HTR3B|HTR6|SLC6A4 | serotonin receptor agonist | Details | |
| C03587 | BRD-K93806173 | N-MPPP | opioid receptor agonist | Details | ||
| C03588 | BRD-K97360717 | N-oxydiethylenebenzothiazole-2-sulfenamide | Details | |||
| C03589 | BRD-K39693230 | N-salicoylaminophenol | ribonucleotide reductase inhibitor | Details | ||
| C03590 | BRD-K36804890 | NAB-2 | NEDD4 | ubiquitin ligase transport promoter | Details | |
| C03591 | BRD-K65146499 | nabumetone | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C03592 | BRD-A11132253 | nadide | AHCY|AKR1A1|ALDH2|BLVRA|DHPS|DLD|GALE|HMGCR|HSD17B1|HSD17B4|IMPDH2|MGAM|P2RY11|SORD|TRPM2 | electron acceptor | Details | |
| C03593 | BRD-A24397426 | nadifloxacin | bacterial DNA gyrase inhibitor | Details | ||
| C03594 | BRD-A87606379 | nadolol | ADRB1|ADRB2|ADRB3 | adrenergic receptor antagonist | Details | |
| C03595 | BRD-M06409173 | NADPH | AASS|DPYD|GHSR|TXNRD1 | Details | ||
| C03596 | BRD-A71262238 | nafadotride | DRD2|DRD3|HTR1A | dopamine receptor antagonist | Details | |
| C03597 | BRD-K06674495 | nafamostat | ASIC1|ASIC2|ASIC3|C1R|PRSS1|TPSAB1|TRPM7 | serine protease inhibitor | Details | |
| C03598 | BRD-K18574842 | nafcillin | CYP1A2|CYP3A4|SLC22A6 | bacterial cell wall synthesis inhibitor | Details | |
| C03599 | BRD-A67862938 | naftidrofuryl | adrenergic receptor antagonist | Details | ||
| C03600 | BRD-K74141488 | naftifine | SQLE | fungal squalene epoxidase inhibitor | Details |