CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C01101 | BRD-K52117081 | ceftazidime | bacterial cell wall synthesis inhibitor | Details | ||
| C01102 | BRD-K11124378 | ceftibuten | bacterial cell wall synthesis inhibitor | Details | ||
| C01103 | BRD-K82960980 | ceftiofur | bacterial cell wall synthesis inhibitor | Details | ||
| C01104 | BRD-K04301924 | ceftizoxim | bacterial cell wall synthesis inhibitor | Details | ||
| C01105 | BRD-K96734425 | ceftriaxone | bacterial cell wall synthesis inhibitor | Details | ||
| C01106 | BRD-K02733959 | cefuroxime | bacterial cell wall synthesis inhibitor | Details | ||
| C01107 | BRD-A22303829 | cefuroxime-axetil | bacterial cell wall synthesis inhibitor | Details | ||
| C01108 | BRD-K02637541 | celecoxib | CA12|PDPK1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C01109 | BRD-A95602221 | celiprolol | ADRA2A|ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C01110 | BRD-K31329721 | centazolone | monoamine oxidase inhibitor | Details | ||
| C01111 | BRD-A28958257 | centpropazine | inositol monophosphatase inhibitor | Details | ||
| C01112 | BRD-K20722021 | CEP-32496 | BRAF|RAF1 | RAF inhibitor | Details | |
| C01113 | BRD-K37237504 | CEP-33779 | JAK2 | JAK inhibitor | Details | |
| C01114 | BRD-K72827473 | CEP-37440 | ALK | ALK tyrosine kinase receptor inhibitor | Details | |
| C01115 | BRD-K90733503 | cephalexin | bacterial cell wall synthesis inhibitor | Details | ||
| C01116 | BRD-K68904758 | cephalomannine | DNA polymerase inhibitor | Details | ||
| C01117 | BRD-A44936478 | cephalosporin-c-zn | bacterial cell wall synthesis inhibitor | Details | ||
| C01118 | BRD-K28210218 | cephalothin | bacterial cell wall synthesis inhibitor | Details | ||
| C01119 | BRD-K49880111 | cephapirin | bacterial cell wall synthesis inhibitor | Details | ||
| C01120 | BRD-K96194081 | cepharanthine | NFkB pathway inhibitor | Details | ||
| C01121 | BRD-A90807417 | cephradine | bacterial cell wall synthesis inhibitor | Details | ||
| C01122 | BRD-K41707108 | ceramide | phosphoenolpyruvate carboxylase activator; serine/threonine protein phosphatase activator | Details | ||
| C01123 | BRD-K22149900 | ceritinib | ALK|FLT3|IGF1R|INSR|TSSK1B | ALK tyrosine kinase receptor inhibitor | Details | |
| C01124 | BRD-K52075040 | cerulenin | FASN | fatty acid synthase inhibitor | Details | |
| C01125 | BRD-K86954340 | cetaben | PPARA | cholesterol inhibitor; ACAT inhibitor | Details | |
| C01126 | BRD-K94863486 | cetilistat | PNLIP | triacylglycerol lipase inhibitor | Details | |
| C01127 | BRD-A42571354 | cetirizine | HRH1 | histamine receptor antagonist | Details | |
| C01128 | BRD-K47079459 | cetrimonium | Details | |||
| C01129 | BRD-K76315403 | cetrorelix | GNRHR|LHCGR | gonadotropin releasing factor hormone receptor antagonist | Details | |
| C01130 | BRD-K87700323 | cetylpyridinium | Details | |||
| C01131 | BRD-M98279124 | cevimeline | CHRM1|CHRM3 | acetylcholine receptor agonist | Details | |
| C01132 | BRD-A02473266 | cevipabulin | TUBB | microtubule stimulant; tubulin polymerization inhibitor | Details | |
| C01133 | BRD-A47940219 | CE3F4 | RAPGEF3 | rap guanine nucleotide exchange factor inhibitor | Details | |
| C01134 | BRD-K64341947 | CFM-1571 | guanylate cyclase activator | Details | ||
| C01135 | BRD-K42859542 | CFM-2 | glutamate receptor antagonist | Details | ||
| C01136 | BRD-K72004355 | CFTRinh-172 | CFTR | chloride channel blocker | Details | |
| C01137 | BRD-K52396582 | CF102 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor agonist | Details | |
| C01138 | BRD-K48888725 | CG-400549 | FABI inhibitor | Details | ||
| C01139 | BRD-K82028950 | CGH2466 | ADORA1|ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C01140 | BRD-A50737080 | CGK-733 | ATM|ATR | ATM kinase inhibitor; ATR kinase inhibitor | Details | |
| C01141 | BRD-K79584249 | CGM097 | MDM2 | MDM inhibitor | Details | |
| C01142 | BRD-A40084411 | CGP-12177 | ADRB1|ADRB2|ADRB3 | adrenergic receptor agonist | Details | |
| C01143 | BRD-K95851186 | CGP-13501 | GABBR1 | GABA receptor modulator | Details | |
| C01144 | BRD-A31575449 | CGP-20712A | ADRB1|ADRB3 | adrenergic receptor antagonist | Details | |
| C01145 | BRD-A35623999 | CGP-37157 | SLC8A1 | mitochondrial Na+/Ca2+ exchanger antagonist; sodium/calcium exchange inhibitor | Details | |
| C01146 | BRD-A90272038 | CGP-37849 | GRIN2A|GRIN2B|GRIN2C|GRIN2D | glutamate receptor antagonist | Details | |
| C01147 | BRD-K13087974 | CGP-52411 | EGFR | EGFR inhibitor | Details | |
| C01148 | BRD-K32292990 | CGP-53353 | EGFR|PRKCB | EGFR inhibitor; PKC inhibitor | Details | |
| C01149 | BRD-A74208568 | CGP-54626 | GABBR1|GABBR2|KCTD12|KCTD16|KCTD8 | GABA receptor antagonist | Details | |
| C01150 | BRD-A89672324 | CGP-55845 | GABBR1|GABBR2|KCTD12|KCTD16|KCTD8 | GABA receptor antagonist | Details | |
| C01151 | BRD-K42500029 | CGP-57380 | AURKB|LCK|MKNK1|MKNK2|SGK1 | MAP kinase inhibitor | Details | |
| C01152 | BRD-K79090631 | CGP-60474 | CDK1|CDK2 | CDK inhibitor | Details | |
| C01153 | BRD-K34321528 | CGP-71683 | NPY5R | neuropeptide receptor antagonist | Details | |
| C01154 | BRD-K56239177 | CGP-74514 | CDK1 | CDK inhibitor | Details | |
| C01155 | BRD-K60946979 | CGP-78608 | glutamate receptor antagonist | Details | ||
| C01156 | BRD-K65786282 | CGP-7930 | GABBR1 | GABA receptor modulator | Details | |
| C01157 | BRD-K49049886 | CGS-15943 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor antagonist | Details | |
| C01158 | BRD-K68103045 | CGS-20625 | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6 | benzodiazepine receptor agonist; GABA benzodiazepine site receptor partial agonist | Details | |
| C01159 | BRD-K12614344 | CGS-21680 | ADORA1|ADORA2A|ADORA2B|ADORA3 | adenosine receptor agonist | Details | |
| C01160 | BRD-K54093161 | CGS-9896 | GABRA1|GABRB2|GABRG2 | GABA receptor antagonist | Details | |
| C01161 | BRD-K24820488 | CH-170 | Details | |||
| C01162 | BRD-K11683436 | CH-5183284 | FGFR1|FGFR2|FGFR3 | fibroblast growth factor inhibitor | Details | |
| C01163 | BRD-K60302405 | CHC | SLC16A1 | monocarboxylate transporter inhibitor | Details | |
| C01164 | BRD-K18135438 | chenodeoxycholic-acid | HSD11B1|NR1H4 | 11-beta hydroxysteroid dehydrogenase inhibitor; FXR agonist | Details | |
| C01165 | BRD-K34508702 | CHF5074 | PSEN1 | gamma secretase modulator | Details | |
| C01166 | BRD-K56483981 | chicago-sky-blue-6b | MIF | glutamate inhibitor; macrophage migration inhibiting factor inhibitor | Details | |
| C01167 | BRD-K28537285 | chidamide | HDAC10|HDAC3 | HDAC inhibitor | Details | |
| C01168 | BRD-K52284881 | chiniofon | antiprotozoal agent | Details | ||
| C01169 | BRD-K02241333 | CHIR-124 | CHEK1 | CHK inhibitor | Details | |
| C01170 | BRD-K42973005 | CHIR-98014 | GSK3A|GSK3B | glycogen synthase kinase inhibitor | Details | |
| C01171 | BRD-K16189898 | CHIR-99021 | CDK1|GSK3A|GSK3B|MAPK1 | glycogen synthase kinase inhibitor | Details | |
| C01172 | BRD-A98174560 | chloralose | Details | |||
| C01173 | BRD-K29458283 | chlorambucil | DNA inhibitor | Details | ||
| C01174 | BRD-K93546328 | chloramine-t | Details | |||
| C01175 | BRD-K08111712 | chloramphenicol | CD55 | bacterial 50S ribosomal subunit inhibitor | Details | |
| C01176 | BRD-K96424892 | chloramphenicol-palmitate | protein synthesis inhibitor | Details | ||
| C01177 | BRD-K25209357 | chloramphenicol-sodium-succinate | protein synthesis inhibitor | Details | ||
| C01178 | BRD-K21452876 | chlorazanil | Details | |||
| C01179 | BRD-A57133233 | chlorcyclizine | HRH1 | histamine receptor antagonist | Details | |
| C01180 | BRD-K89409436 | chlorfenson | other antifungal | Details | ||
| C01181 | BRD-K52256627 | chlorhexidine | membrane integrity inhibitor | Details | ||
| C01182 | BRD-K01653460 | chlorindanol | Details | |||
| C01183 | BRD-K61802864 | chlorindione | Details | |||
| C01184 | BRD-K18030938 | chlorisondamine-diiodide | CHRNA1 | acetylcholine receptor antagonist | Details | |
| C01185 | BRD-A01593789 | chlormadinone-acetate | PGR | 5 alpha reductase inhibitor | Details | |
| C01186 | BRD-A20348246 | chlormezanone | GABRA1|TSPO | GABA receptor modulator | Details | |
| C01187 | BRD-K60443845 | chlormidazole | fungal lanosterol demethylase inhibitor | Details | ||
| C01188 | BRD-K39495750 | chlorobutanol | Details | |||
| C01189 | BRD-K89056082 | chlorocresol | ryanodine receptor activator | Details | ||
| C01190 | BRD-K47114202 | chlorogenic-acid | SLC37A4 | antioxidant | Details | |
| C01191 | BRD-A63866086 | chlorophyllide-cu-complex-na-salt | Details | |||
| C01192 | BRD-K23728266 | chlorophyllin | Details | |||
| C01193 | BRD-A92960111 | chlorophyllin-copper | cytochrome P450 inhibitor | Details | ||
| C01194 | BRD-K86864073 | chloroprocaine | ATP1A1|CHRNA10|GRIN3A|HTR3A|SCN10A|SLC6A3 | sodium channel blocker | Details | |
| C01195 | BRD-K83257731 | chloropyramine | HRH1 | histamine receptor antagonist | Details | |
| C01196 | BRD-A91699651 | chloroquine | GSTA2|MRGPRX1|TLR9|TNF | antimalarial agent | Details | |
| C01197 | BRD-K88682005 | chlorothiazide | CA1|CA2|CA4|SLC12A3 | diuretic | Details | |
| C01198 | BRD-K04358951 | chlorothymol | Details | |||
| C01199 | BRD-K27062708 | chlorotrianisene | ESR1|ESR2 | estrogenic hormone | Details | |
| C01200 | BRD-K17075857 | chloroxine | OPRK1 | opioid receptor antagonist | Details |