CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
stats1
stats2
6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C02301 | BRD-K38852836 | ganetespib | HSP90AA1 | HSP inhibitor | Details | |
| C02302 | BRD-A30703952 | ganglioside-gm1 | Details | |||
| C02303 | BRD-K64451768 | GANT-58 | GLI1 | GLI antagonist | Details | |
| C02304 | BRD-K09485525 | GANT-61 | GLI1|GLI2 | GLI antagonist | Details | |
| C02305 | BRD-K77038618 | garenoxacin | TOP2A | topoisomerase inhibitor | Details | |
| C02306 | BRD-K81613478 | gastrodin | Details | |||
| C02307 | BRD-A74980173 | gatifloxacin | bacterial DNA gyrase inhibitor | Details | ||
| C02308 | BRD-K81981783 | gavestinel | GLRB | glutamate receptor antagonist | Details | |
| C02309 | BRD-K92015269 | GBR-12783 | dopamine uptake inhibitor | Details | ||
| C02310 | BRD-K50135270 | GBR-12935 | AGTR1|SLC6A3 | dopamine uptake inhibitor | Details | |
| C02311 | BRD-K92577649 | GBR-13069 | SLC6A3 | dopamine uptake inhibitor | Details | |
| C02312 | BRD-K71480163 | GDC-0068 | AKT1|AKT2|AKT3|PRKG1 | AKT inhibitor | Details | |
| C02313 | BRD-K68938568 | GDC-0152 | BIRC2|BIRC3|BIRC7|XIAP | XIAP inhibitor | Details | |
| C02314 | BRD-K43187018 | GDC-0349 | PIK3CA | Pim kinase inhibitor | Details | |
| C02315 | BRD-K46908090 | GDC-0623 | MEK inhibitor | Details | ||
| C02316 | BRD-K61923022 | GDC-0810 | ESR1 | selective estrogen receptor destabilizer | Details | |
| C02317 | BRD-A30984645 | GDC-0834 | BTK | Bruton's tyrosine kinase (BTK) inhibitor | Details | |
| C02318 | BRD-K67578145 | GDC-0879 | BRAF | RAF inhibitor | Details | |
| C02319 | BRD-K52911425 | GDC-0941 | PIK3CA|PIK3CB|PIK3CD|PIK3CG | PI3K inhibitor | Details | |
| C02320 | BRD-K23228615 | GDC-0980 | FGR|MAP3K9|MTOR|PIK3CA|PIK3CB|PIK3CD|PIK3CG|SYK | mTOR inhibitor; PI3K inhibitor | Details | |
| C02321 | BRD-A20830788 | GDC-0994 | MAPK1|MAPK3 | MAP kinase inhibitor | Details | |
| C02322 | BRD-K02703275 | gedunin | HSP90AA1 | HSP inhibitor | Details | |
| C02323 | BRD-K64052750 | gefitinib | EGFR | EGFR inhibitor | Details | |
| C02324 | BRD-K43570081 | geldanamycin | HSP90AA1|HSP90AB1 | HSP inhibitor | Details | |
| C02325 | BRD-K43890836 | gemcadiol | antilipemic | Details | ||
| C02326 | BRD-K15108141 | gemcitabine | CMPK1|RRM1|RRM2|TYMS | ribonucleotide reductase inhibitor | Details | |
| C02327 | BRD-K09456915 | gemcitabine-elaidate | CMPK1|RRM1|TYMS | DNA synthesis inhibitor; apoptosis inhibitor | Details | |
| C02328 | BRD-K11129031 | gemfibrozil | LPL|PPARA|SLCO1B1|SLCO1B3|SLCO2B1 | lipoprotein lipase activator | Details | |
| C02329 | BRD-A40787240 | gemifloxacin | bacterial DNA gyrase inhibitor | Details | ||
| C02330 | BRD-K28824103 | genipin | choleretic agent | Details | ||
| C02331 | BRD-K57275767 | geniposide | GLP1R | GLP receptor agonist | Details | |
| C02332 | BRD-K73771095 | geniposidic-acid | cyclooxygenase inhibitor | Details | ||
| C02333 | BRD-K43797669 | genistein | CFTR|ESR1|ESR2|ESRRA|ESRRB|ESRRG|NCOA1|NCOA2|PPARG|PTK2B|TOP2A|TRPC5 | tyrosine kinase inhibitor | Details | |
| C02334 | BRD-A89445950 | gentamycin | HSPA8|LRP2 | bacterial 50S ribosomal subunit inhibitor | Details | |
| C02335 | BRD-K33131085 | gentiopicrin | GRIN2B | glutamate receptor downregulator | Details | |
| C02336 | BRD-K70693421 | genz-123346 | UGCG | glucosylceramidase inhibitor | Details | |
| C02337 | BRD-K99475619 | genz-644282 | TOP1 | topoisomerase inhibitor | Details | |
| C02338 | BRD-A04447196 | gepefrine | adrenergic receptor agonist | Details | ||
| C02339 | BRD-A56754222 | gepon | Details | |||
| C02340 | BRD-K02780233 | geranyl-farnesylacetate | mucin production enhancer | Details | ||
| C02341 | BRD-K97197005 | gestodene | contraceptive agent | Details | ||
| C02342 | BRD-K97472745 | gestrinone | AR|ESR1|PGR | progesterone receptor antagonist | Details | |
| C02343 | BRD-K31342827 | GF109203X | PDPK1|PIM1|PRKCI|PRKCZ | PKC inhibitor | Details | |
| C02344 | BRD-A25625670 | GGsTop | GGT1 | gamma glutamyltransferase Inhibitors | Details | |
| C02345 | BRD-K19669037 | GGTI-298 | CDKN1A | GGTase inhibitor | Details | |
| C02346 | BRD-K22588750 | gidazepam | GABA benzodiazepine site receptor agonist | Details | ||
| C02347 | BRD-K72280606 | gilteritinib | FLT3 | FLT3 inhibitor | Details | |
| C02348 | BRD-K35687421 | gimeracil | DPYD | dihydropyrimidine dehydrogenase inhibitor | Details | |
| C02349 | BRD-A95121829 | ginkgolide-a | GLRA1|GLRB | GABA receptor antagonist | Details | |
| C02350 | BRD-A08430411 | ginkgolide-b | GLRA1|GLRA2|GLRA3|GLRB|HTR3A|HTR3B | platelet activating factor receptor antagonist | Details | |
| C02351 | BRD-K01942833 | ginsenoside-c-k | PTGS2 | NFkB pathway inhibitor; nitric oxide synthase inhibitor | Details | |
| C02352 | BRD-A84810646 | ginsenoside-rd | calcium channel blocker | Details | ||
| C02353 | BRD-A44511856 | ginsenoside-rg3 | KCNH2 | angiogenesis inhibitor; apoptosis stimulant | Details | |
| C02354 | BRD-K13810148 | givinostat | HDAC1|HDAC2|HDAC3|HDAC4|HDAC5|HDAC6|HDAC7|HDAC8|HDAC9 | HDAC inhibitor | Details | |
| C02355 | BRD-K03827870 | GKA-50 | GCK | glucokinase activator | Details | |
| C02356 | BRD-K79710622 | GKT137831 | NOX1|NOX4 | NADPH oxidase inhibitor | Details | |
| C02357 | BRD-K38272302 | GK921 | TGM2 | transglutaminase inhibitor | Details | |
| C02358 | BRD-A38076815 | glafenine | CFTR | DeltaF508-CFTR Correctors | Details | |
| C02359 | BRD-K34341643 | glasdegib | SMO | hedgehog pathway inhibitor | Details | |
| C02360 | BRD-A61154809 | gliclazide | ABCC8|VEGFA | ATP channel blocker; insulin secretagogue | Details | |
| C02361 | BRD-K34776109 | glimepiride | ABCC8|KCNJ1|KCNJ11 | insulin secretagogue | Details | |
| C02362 | BRD-K12219985 | glipizide | ABCC8|KCNJ10|KCNJ11|PPARG | sulfonylurea | Details | |
| C02363 | BRD-K80396088 | gliquidone | ABCC8|KCNJ10|KCNJ8 | sulfonylurea | Details | |
| C02364 | BRD-K15893360 | GLPG0492 | AR | androgen receptor modulator | Details | |
| C02365 | BRD-K04643927 | GLPG0492-R-enantiomer | AR | androgen receptor modulator | Details | |
| C02366 | BRD-K60150658 | glucaric-acid | Details | |||
| C02367 | BRD-K04288422 | gluconolactone | LCT | Details | ||
| C02368 | BRD-K29918010 | glucosamine | IFNG|IL1B|MMP9|NFKB2|TNF | glycosylated protein precursor | Details | |
| C02369 | BRD-K83896451 | glutamine-(l) | CTPS1|GLUL|GPRC6A|PPAT | Details | ||
| C02370 | BRD-K69346723 | glutathione | ESD|GGT1|GLO1|GLRX|GLRX2|GPX1|GPX2|GPX3|GPX4|GPX5|GPX6|GPX7|GPX8|GSR|GSS|GSTA1|GSTA2|GSTA3|GSTA4|GSTA5|GSTK1|GSTM1|GSTM2|GSTM3|GSTM4|GSTM5|GSTO1|GSTO2|GSTP1|GSTT1|GSTZ1|HAGH|HPGDS|LTC4S|MGST1|MGST2|MGST3|TXNDC12 | antioxidant | Details | |
| C02371 | BRD-K58937086 | glutathione-monoisopropyl-ester | lipid peroxidase inhibitor | Details | ||
| C02372 | BRD-K85066592 | gly-gln | Details | |||
| C02373 | BRD-K36927236 | glyburide | ABCA1|ABCB11|ABCC8|ABCC9|CFTR|CPT1A|KCNJ1|KCNJ11|KCNJ5|KCNJ8|SLCO2B1 | ATP channel blocker; insulin secretagogue; sulfonylurea | Details | |
| C02374 | BRD-A10773072 | glycerol-monolaurate | beta lactamase inhibitor | Details | ||
| C02375 | BRD-K78303961 | glycitein | TNF | tumor necrosis factor release inhibitor | Details | |
| C02376 | BRD-A81233518 | glycopyrrolate | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor antagonist | Details | |
| C02377 | BRD-K69832040 | GMX1778 | NAMPT | NAMPT inhibitor | Details | |
| C02378 | BRD-K97056771 | GNF-2 | ABL1|BCR | Bcr-Abl kinase inhibitor | Details | |
| C02379 | BRD-K87632963 | GNF-5 | ABL1|BCR | Bcr-Abl kinase inhibitor | Details | |
| C02380 | BRD-K19975102 | GNF-5837 | NTRK1|NTRK2|NTRK3 | growth factor receptor inhibitor | Details | |
| C02381 | BRD-K69075588 | GNF-7 | GCK|TNK2 | protein kinase inhibitor; glucokinase inhibitor | Details | |
| C02382 | BRD-K64748124 | GNTI | OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C02383 | BRD-K36984403 | go-6983 | PRKCA|PRKCB|PRKCD|PRKCG|PRKCZ | protein kinase inhibitor | Details | |
| C02384 | BRD-A57886255 | golgicide-a | GBF1 | ARF inhibitor | Details | |
| C02385 | BRD-K69001009 | golvatinib | KDR|MET | VEGFR inhibitor | Details | |
| C02386 | BRD-K96874295 | gonadorelin | GNRHR|GNRHR2 | gonadotropin releasing factor hormone receptor agonist | Details | |
| C02387 | BRD-K99504665 | goserelin-acetate | GNRHR|LHCGR | gonadotropin releasing factor hormone receptor agonist | Details | |
| C02388 | BRD-K19295594 | gossypol | BCL2 | BCL inhibitor; MCL1 inhibitor | Details | |
| C02389 | BRD-K67397687 | GPBAR-A | GPBAR1 | G protein coupled receptor agonist | Details | |
| C02390 | BRD-K44869961 | GPI-1046 | FKBP1A | FKBP inhibitor | Details | |
| C02391 | BRD-A90201073 | GPi-688 | glycogen phosphorylase inhibitor | Details | ||
| C02392 | BRD-K83289131 | GPP-78 | NAMPT | NAMPT inhibitor | Details | |
| C02393 | BRD-K19409553 | GPR120-modulator-1 | FFAR4 | G protein-coupled receptor modulator | Details | |
| C02394 | BRD-K65285700 | GP1a | CNR2 | cannabinoid receptor agonist | Details | |
| C02395 | BRD-K34608650 | GP2a | CNR2 | cannabinoid receptor agonist | Details | |
| C02396 | BRD-K50891186 | GR-103691 | DRD3 | dopamine receptor antagonist | Details | |
| C02397 | BRD-K49945136 | GR-113808 | HTR4 | serotonin receptor antagonist | Details | |
| C02398 | BRD-K11911061 | GR-127935 | HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR6 | serotonin receptor antagonist | Details | |
| C02399 | BRD-K83023055 | GR-135531 | melatonin receptor agonist | Details | ||
| C02400 | BRD-K12120659 | GR-144053 | ITGA2B|ITGB3 | integrin antagonist | Details |