CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of CKD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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6125 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C03301 | BRD-K19180152 | meprobamate | GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ | Details | ||
| C03302 | BRD-K65417056 | meprylcaine | local anesthetic | Details | ||
| C03303 | BRD-A02710418 | meptazinol | BCHE | opioid receptor agonist | Details | |
| C03304 | BRD-K97564742 | mepyramine | HRH1 | histamine receptor antagonist | Details | |
| C03305 | BRD-K45216060 | mequinol | TYR | Details | ||
| C03306 | BRD-K45152786 | merbarone | TOP2A | topoisomerase inhibitor | Details | |
| C03307 | BRD-K21771665 | merbromin | antiseptic | Details | ||
| C03308 | BRD-K91601245 | mercaptopurine | HPRT1|IMPDH1|IMPDH2|PPAT | immunosuppressant; protein synthesis inhibitor; purine antagonist | Details | |
| C03309 | BRD-A43435802 | mercaptosuccinic-acid | Details | |||
| C03310 | BRD-K69726595 | mericitabine | HCV inhibitor | Details | ||
| C03311 | BRD-K09372874 | merimepodib | IMPDH1 | inosine monophosphate dehydrogenase inhibitor | Details | |
| C03312 | BRD-K01612348 | meropenem | bacterial cell wall synthesis inhibitor | Details | ||
| C03313 | BRD-K28849549 | mesalazine | ALOX5|CHUK|IKBKB|MPO|PPARG|PTGS1|PTGS2 | cyclooxygenase inhibitor; lipoxygenase inhibitor; prostanoid receptor antagonist | Details | |
| C03314 | BRD-K49954789 | mesna | antioxidant | Details | ||
| C03315 | BRD-A14395271 | mesoridazine | DRD2|HTR2A | dopamine receptor antagonist | Details | |
| C03316 | BRD-K69688083 | mestinon | ACHE|BCHE | cholinesterase inhibitor | Details | |
| C03317 | BRD-K31920458 | mestranol | ESR1 | estrogen receptor agonist | Details | |
| C03318 | BRD-K91336023 | mesulergine | HTR2A|HTR2B|HTR2C|HTR3A|HTR3B|HTR6|HTR7 | dopamine receptor agonist | Details | |
| C03319 | BRD-K33442414 | meta-cresyl-acetate | Details | |||
| C03320 | BRD-K16474819 | metacetamol | analgesic agent | Details | ||
| C03321 | BRD-K22518984 | metacresol | INS | Details | ||
| C03322 | BRD-K28580965 | metafolin | AMT | Details | ||
| C03323 | BRD-K76812510 | metamizole | PTGS1 | cyclooxygenase inhibitor; opioid receptor agonist | Details | |
| C03324 | BRD-K95701999 | metaphit | phencyclidine receptor acylator | Details | ||
| C03325 | BRD-A07780951 | metaproterenol | ADRB2 | adrenergic receptor agonist | Details | |
| C03326 | BRD-K96253961 | metaraminol | ADRA1A | adrenergic receptor agonist | Details | |
| C03327 | BRD-K27182532 | metatinib | ABL1|BCR | Bcr-Abl kinase inhibitor | Details | |
| C03328 | BRD-A94709349 | metaxalone | muscle relaxant | Details | ||
| C03329 | BRD-A78277353 | metazosin | ADRA1A | adrenergic receptor antagonist | Details | |
| C03330 | BRD-A38218502 | metenkephalin | OPRD1 | immunostimulant | Details | |
| C03331 | BRD-K56699285 | metergoline | HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR5A|HTR6|HTR7 | dopamine receptor agonist; serotonin receptor antagonist | Details | |
| C03332 | BRD-K79602928 | metformin | ACACB|PRKAB1 | insulin sensitizer | Details | |
| C03333 | BRD-A18056626 | methacholine | CHRM2|CHRM3|CHRM4 | acetylcholine receptor agonist | Details | |
| C03334 | BRD-A49035384 | methacycline | protein synthesis inhibitor | Details | ||
| C03335 | BRD-K53896891 | methanesulfonyl-fluoride | ACHE | acetylcholinesterase inhibitor | Details | |
| C03336 | BRD-K09859624 | methantheline | CHRM1|HRH2 | acetylcholine receptor antagonist | Details | |
| C03337 | BRD-K47323024 | methapyrilene | HRH1 | histamine receptor antagonist | Details | |
| C03338 | BRD-K88143662 | metharbital | CHRNA4|CHRNA7|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GRIA2|GRIK2 | GABA receptor modulator | Details | |
| C03339 | BRD-K13356952 | methazolamide | CA1|CA12|CA14|CA2|CA4|CA7 | carbonic anhydrase inhibitor | Details | |
| C03340 | BRD-K30114692 | methenamine | bacterial DNA inhibitor | Details | ||
| C03341 | BRD-K02764365 | methiazole | anthelmintic agent | Details | ||
| C03342 | BRD-K34388247 | methicillin | bacterial cell wall synthesis inhibitor | Details | ||
| C03343 | BRD-K54416256 | methimazole | TPO | antithyroid agent | Details | |
| C03344 | BRD-A39515206 | methionine | BHMT|BHMT2|METAP2|MTR|MTRR | Details | ||
| C03345 | BRD-A32172948 | methiopril | ACE | angiotensin converting enzyme inhibitor | Details | |
| C03346 | BRD-A31521121 | methocarbamol | CA1 | muscle relaxant | Details | |
| C03347 | BRD-K34591242 | methoprene-(s) | Details | |||
| C03348 | BRD-K59456551 | methotrexate | DHFR | dihydrofolate reductase inhibitor | Details | |
| C03349 | BRD-A39189014 | methoxamine | ADRA1A|ADRA1B|ADRA1D | adrenergic receptor agonist | Details | |
| C03350 | BRD-K63430059 | methoxsalen | CYP1A1|CYP1A2|CYP2A13|CYP2A6|CYP3A4 | DNA synthesis inhibitor | Details | |
| C03351 | BRD-K79277568 | methoxyamine | APEX1 | DNA repair enzyme inhibitor | Details | |
| C03352 | BRD-K06152156 | methoxyflurane | ATP2C1|ATP5D|GABRA1|GABRA2|GABRA3|GABRA4|GABRA5|GABRA6|GABRB1|GABRB2|GABRB3|GABRD|GABRE|GABRG1|GABRG2|GABRG3|GABRP|GABRQ|GLRA1|GLRB|GRIA1|KCNA1|MT-ND1 | membrane permeability inhibitor | Details | |
| C03353 | BRD-A21474126 | methoxyphenamine | adrenergic receptor agonist | Details | ||
| C03354 | BRD-K48619321 | methscopolamine | CHRM1|CHRM2|CHRM3 | acetylcholine receptor antagonist | Details | |
| C03355 | BRD-A57592049 | methsuximide | CACNA1G|CACNA1H|CACNA1I | T-type calcium channel binder | Details | |
| C03356 | BRD-A95340155 | methyclothiazide | CA1|CA2|CA4|SLC12A1|SLC12A3 | chloride reabsorption inhibitor | Details | |
| C03357 | BRD-K01292611 | methyl-aminolevulinate | FCGR1A|FECH | oxidizing agent | Details | |
| C03358 | BRD-K10132944 | methyl-nicotinate | Details | |||
| C03359 | BRD-K10103010 | methyl-salicylate | Details | |||
| C03360 | BRD-A52460047 | methylatropine-nitrate | CHRM1 | acetylcholine receptor antagonist | Details | |
| C03361 | BRD-K46531780 | methylbenzethonium-chloride | other antibiotic | Details | ||
| C03362 | BRD-K48578705 | methyldopa | ADRA2A|ADRA2B|ADRA2C|DDC | adrenergic receptor agonist | Details | |
| C03363 | BRD-K82259334 | methyldopate | Details | |||
| C03364 | BRD-K16406336 | methylene-blue | ACHE | guanylyl cyclase inhibitor; nitric oxide production inhibitor | Details | |
| C03365 | BRD-K34685430 | methylergometrine | DRD1|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C03366 | BRD-K43192255 | methyllycaconitine | CHRNA7 | acetylcholine receptor antagonist | Details | |
| C03367 | BRD-K33732501 | methylnaltrexone | OPRD1|OPRK1|OPRM1 | opioid receptor antagonist | Details | |
| C03368 | BRD-K78321730 | methylparaben | other antifungal | Details | ||
| C03369 | BRD-A19585813 | methylphenidate | SLC6A2|SLC6A3|SLC6A4 | dopamine norepinephrine reuptake inhibitor | Details | |
| C03370 | BRD-K35240538 | methylprednisolone | NR3C1 | glucocorticoid receptor agonist | Details | |
| C03371 | BRD-K24452555 | methylprednisolone-aceponate | NR3C1 | anti-inflammatory agent; glucocorticoid receptor agonist | Details | |
| C03372 | BRD-A45044890 | methylprednisolone-sodium-succinate | glucocorticoid receptor agonist | Details | ||
| C03373 | BRD-K11900042 | methylthiouracil | Details | |||
| C03374 | BRD-K35941380 | methysergide | HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR5A|HTR6|HTR7 | serotonin receptor antagonist | Details | |
| C03375 | BRD-K58265391 | meticrane | diuretic | Details | ||
| C03376 | BRD-A99388803 | metipranolol | ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C03377 | BRD-K83766205 | metirosine | TH | tyrosine hydroxylase inhibitor | Details | |
| C03378 | BRD-A07932845 | metitepine | HTR1A|HTR1B|HTR1D|HTR1E|HTR1F|HTR2A|HTR2B|HTR2C|HTR5A|HTR6|HTR7 | anti-HCVE2 | Details | |
| C03379 | BRD-A33711280 | metixene | CHRM1|CHRM2|CHRM3|CHRM4|CHRM5 | acetylcholine receptor antagonist | Details | |
| C03380 | BRD-K75641298 | metoclopramide | CHRM1|DRD2|HTR3A|HTR3B|HTR4 | dopamine receptor antagonist; serotonin receptor antagonist | Details | |
| C03381 | BRD-K16484091 | metocurine | CHRM2|CHRNA2 | acetylcholine receptor antagonist | Details | |
| C03382 | BRD-A61793559 | metolazone | SLC12A3 | carbonic anhydrase inhibitor | Details | |
| C03383 | BRD-A03623303 | metoprolol | ADRB1|ADRB2 | adrenergic receptor antagonist | Details | |
| C03384 | BRD-A71725768 | metoxibutropate | PTGS1|PTGS2 | cyclooxygenase inhibitor | Details | |
| C03385 | BRD-A22101059 | metrifonate | ACHE | acetylcholinesterase inhibitor | Details | |
| C03386 | BRD-A45543382 | metrizamide | radiopaque medium | Details | ||
| C03387 | BRD-K99241550 | metrizoic-acid | radiopaque medium | Details | ||
| C03388 | BRD-K52020312 | metronidazole | CYP2C9|CYP3A4 | DNA inhibitor | Details | |
| C03389 | BRD-K46862739 | metyrapone | CYP11B1 | cytochrome P450 inhibitor | Details | |
| C03390 | BRD-A05674712 | mevalonic-d,-l-acid-lactone | Details | |||
| C03391 | BRD-K94441233 | mevastatin | HMGCR | HMGCR inhibitor | Details | |
| C03392 | BRD-K18613660 | mexeneone | Details | |||
| C03393 | BRD-A64092382 | mexiletine | AHR|SCN4A|SCN5A | sodium channel blocker | Details | |
| C03394 | BRD-K45114938 | mezlocillin | bacterial cell wall synthesis inhibitor | Details | ||
| C03395 | BRD-A63444178 | ME0328 | PARP3 | PARP inhibitor | Details | |
| C03396 | BRD-K34328244 | MF-101 | CYP19A1|XDH | estrogen receptor agonist | Details | |
| C03397 | BRD-K60230970 | MG-132 | PSMB1 | proteasome inhibitor | Details | |
| C03398 | BRD-K03128577 | MG-624 | CHRNA7 | acetylcholine receptor antagonist | Details | |
| C03399 | BRD-K56277358 | MGCD-265 | AXL|MET | VEGFR inhibitor | Details | |
| C03400 | BRD-K26726854 | MI-14 | PI4KB | PI4K inhibitor | Details |